There are
some significant issues being raised about the procedures used to guarantee the scientific integrity of this research despite the unavoidable involvement of industries with an interest in the outcome.
Not exact matches
Examples of these risks, uncertainties and other factors include, but
are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to
raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the
significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation
issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
This
is a question which will surely need to
be considered by philosophers who have an interest in the very
significant issues raised by Stapp's work.
And while several
issues collided here, maybe the most
significant question
raised is this: Should we
be looking for the «most Christian» — or most moral — candidate they can find?
Hunt said that the revelation over the hacking of Milly Dowler's phone
was significant for him as it
raised concerns about a corporate governance
issue.
If a
significant number of backbenchers cause a fuss about the treatment, it will
be a good way to
raise the profile of the
issue within government.
If he does
raise the
issue, it will
be to wind the prime minister up about the
significant chunk of the Tory party which
is desperately opposed to the measure.
Legislators currently make $ 79,500 per year, though a compensation commission has recently begun examining the
issue and
is likely to recommend
significant raises for lawmakers, who have not seen a
raise in 16 years.
Cuomo's health commissioner, Dr. Howard Zucker says as he examined numerous completed and still on going studies on fracking's effects on drinking water, air quality and other health
issues, several «red flags»
were raised, and he says he has «identified
significant health risks in the current data» that have not
been answered by conclusive long term studies with «large population pools».
It should
be noted that a
significant proportion of former smokers in our sample set exhibited low FEV1 levels,
raising the possibility that airflow obstruction may
be a confounding
issue in this analysis.
She
's also a goodwill ambassador for the U.N. Environmental Program and
is very active in
raising awareness about
significant social and environmental
issues.
In spite of these
significant problems, however, the movie
raises important
issues of institutional failure and faith, and with fine supporting performances from Chris O'Dowd, Aidan Gillen, Isaach De Bankolé, Marie - Josée Croze, Orla O'Rourke and even * gasp * Domhnall Gleeson (Brendan's son, and an actor I usually find unbearable to watch, but who here
is very good), Calvary has many reasons to see it, even if the sum total of its quality elements do not help it transcend its flaws.
Meanwhile, Engineering UK tells us that by 2022 we will need 1.82 million new engineers, whilst the CBI's campaign
Raising Ambition for All
is based on
significant shortfalls in young people's «work readiness», an
issue addressed by Inspire the Future, the UK Commission for Employment and Skills» programme.
This describes how the work will
be undertaken, how
issues raised from pre ‑ construction information will
be dealt with, and
significant risks controlled.
The
issues raised in this book not only
are significant for lawyers and legal scholars, who
are the chief authors of the book's chapters, but
are also topics pertinent to the lives of scholars and practitioners of citizenship education.
The system appears to
be designed to help Hartford and a handful of other towns, but
raises significant equity
issues.
Ignoring their surplus cash / investments for a minute — the only thing missing operationally from this business
is sustained /
significant success on the fund -
raising front — now
is the ideal time I believe to remedy / attack that
issue, as I've pointed out.
While there may
be breeders that take precaution to avoid inbreeding (which often leads to
significant health
issues), and
are selective with the dogs they do breed, making sure to
raise them in loving environments, there
is no definitive «rule» that guarantees these animals won't suffer from health or behavioral problems early or later on.
Given the domestic hurdles facing Obama, the inability to
raise significant funds for the Green Climate Fund and China's long farewell to its growth in carbon emissions, we may still
be another decade away from seeing this
issue turn around.
«While the Paris Agreement does not address the
issue of climate engineering expressly, the target of limiting global average temperature rise to no more than 2 °C (a goal that appears unlikely to
be achieved in the absence of
significant amounts of carbon removal)
raises questions with respect to how the
issue of carbon dioxide removal (CDR) and solar radiation management (SRM) technologies may
be addressed under the Paris Agreement.
My guess
is that EPA took this action to propose repealing the CPP because it wants to repeal the CPP but does not wish to
raise the fundamental scientific
issues posed by the EF — particularly whether CO2 has a
significant effect on global temperatures.
More broadly, the Moot Court Programme
is also a tool for
raising the profile of freedom of expression by bringing informed and effective debate and discussion on
significant issues of information flows and technology to many parts of the world.
The cases encompassed
significant reputational and domestic political
issues for the company and its senior officers and former officers: Questions
were raised about the matter in the national Parliament.
That
was the question at the heart of a motion Superior Court Justice Douglas Gray said
raises, «
significant issues of policy.»
The Chief Justice of Canada, the Right Honourable Beverley McLachlin, addressed the latter in her recent lecture to the Canadian Bar Association, but I do not perceive that she or anyone else in the legal community have addressed the fundamental
issue that the SRL phenomenon
raises: the right to participate in the making of common law; the ability to put a set of interests before the courts that hitherto have not
been able to afford to
be there — and thus, a rather
significant challenge to the validity of the whole body of common law as it stands.
While the Statutory Accident Benefit regime may give a right to an accident victim to challenge the wrongful denial of a benefit, where the cost of pursuing such a remedy
is prohibitive, this
raises significant issues as to access to justice that have yet to
be addressed.
The Committee identified
significant issues that
are raised when retired judges return to practice.
The appeal
raised significant legal
issues never before decided by the court, including whether a domain name can
be considered property that
is subject to seizure under Kentucky law and whether a domain name can
be considered a gambling device under the law.
This
is in accordance with the Supreme Court of Canada's recent pronouncement that a law previously adjudicated «may
be revisited if new legal
issues are raised as a consequence of
significant developments in the law, or if there
is a change in the circumstances or evidence that fundamentally shifts the parameters of the debate».
According to Executive Order 12866, a regulatory action
is «
significant» if it meets any one of a number of specified conditions, including having an annual effect on the economy of $ 100 million or more adversely affecting in a material way a sector of the economy, competition, or jobs, or if it
raises novel legal or policy
issues.
I'll leave it that if, in fact, you have first hand, not publicly available, information about what a judge or judges actually think about the
issues involved beyond what they've written in published reasons, then that
raises a very
significant question about how you got it and who has
been doing things that he or she ought not have to have.
Justice Kirby's dissent should
be examined carefully as it
raises a number of
significant issues that the government and the broader public should consider.
Joint custody requires the parents discuss and cooperate on all
significant issues regarding how their child
is raised.
Deep resentments over the share of childcare and housework, differing expectations over the amount of sex they should have, and fundamental disagreements over how to
raise children
are just some of the
issues that lead to
significant conflict for many couples over time.
Other
significant issues being discussed for reforms include
raising the required investment amounts and introducing more oversight to reduce incidents of sponsor fraud or misappropriated funds.