Sentences with phrase «significant marker of»

New research indicates that body shape could be a more significant marker of health than weight or BMI.

He could even guide his side to glory on French soil which would serve as a significant marker of his ability.

Wish in the future a panel could be done, that would be able to identify all the significant markers of disease and performance!

Not exact matches

In a study of 20 women ages 40 - 70 with inflammatory osteoarthritis, the researchers found that drinking tart cherry juice twice daily for three weeks led to significant reductions in important inflammation markers - especially for women who had the highest inflammation levels at the start of the study.

Senna edged out Prost in the F1 Drivers» Championship, but even more significant was the margin of victory the MP4 / 4 delivered over its competitors, often lapping not only the back markers but the entire field.

The researchers found that patient's acuity, or level of illness, was not a significant marker in their subsequent quality of life.

By analyzing genetic markers specific to sweet potatoes in both modern samples of the plant and older herbarium specimens, the researchers discovered significant differences between varieties found in the western Pacific versus the eastern Pacific.

Even apparently healthy teenagers showed significant improvements in markers which are indicators of cardiovascular health, according to research by the University of Exeter.

But he says both cases are bolstered by (also less - than - significant) data from neighboring markers, which appear to be shared at higher rates between pairs of brothers.

Analysis of an additional set of 25 North American and Swedish families with markers in this region resulted in significant evidence of linkage in the combined set of 91 families.

In a study of 1,979 overweight and obese adults in the UK, people who lost 5 % or more of their initial body weight over four years showed significant changes in markers of physical health, but were more likely to report depressed mood than those who stayed within 5 % of their original weight.

At present, the most common, sporadic form of Alzheimer's disease is difficult to diagnose until symptoms are readily apparent and significant damage to the brain has occurred; findings from this study may provide clues to suitable diagnostic markers.

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

In addition, p - tau correlated with a significant reduction of post-synaptic markers, such as GluN2A, GluN2B, GluA1, GluA2, Drebrin, and PSD - 95, in P301L mice.

SO, they had suggested the inhibition of cyclin Dl / CDK4 activity might be important in considering drugs of future therapies [25], also, they reported that Cyclin D1 was considered as a significant prognostic marker.

It's potential as a biomarker of disease and an early objective marker of treatment response is genuine but still to be realized.Resting - state functional magnetic resonance imaging has made some strides in the clinical realm but significant advances are required before it can be used in a meaningful way at the single - patient level.

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

To explore the possibility that frailty (which is associated with both low cholesterol and death28 29) could confound these results, we did a sensitivity analysis adjusting our Cox models (table 4 ⇑) for two known markers of frailty (changes in body weight and changes in systolic blood pressure).28 29 30 These adjustments did not materially change the effect estimates, which remained significant in both groups.

As seen in cells dissected from colonies, significant numbers of cells coexpressed lineage specific markers along with pluripotency genes.

The Parkinson's Progression Markers Initiative (PPMI) is a landmark observational clinical study to comprehensively evaluate cohorts of significant interest using advanced imaging, biologic sampling and clinical and behavioral assessments to identify biomarkers of Parkinson's disease progression.

Their gene expression analysis throughout the protocol matched that of a previously published profile for hESCs [24], which included the significant upregulation of mesodermal and chondrogenic markers (PDGFRB, SOX6, SOX9, ACAN, COL2A1 types A and B), with the more mature COL2A1 type B splice variant [42] being more highly expressed by the end of stage 3.

We extensively analyzed various surface markers (e.g., CD2, CD5, HSA, CD25, class I MHC, etc.) of each stage of thymocyte development, but we did not observe significant differences between Gasp + / + and Gasp − / − thymocytes.

Consistent with this observation of MELK overexpression in BBC, we found that MELK expression in breast tumors has a significant inverse correlation with the expression of luminal markers, including estrogen and progesterone receptors (ER, PR)(Figure 2F, Figure 2 — figure supplement 1F).

Although they didn't find any significant and definitive probiotic effect from eating the olives on the participants» health, they found evidence for important anti-inflammatory and antioxidant effects in the form of a decreased inflammatory factor called interleukine - 6 (IL - 6) and a free radical marker known as malondialdehyde (MDA).

When researchers looked at the diets of more than 3,000 European men, they found for those who had the highest intake of fruit, vegetables, and vitamin C, there was a significant decrease in inflammation and inflammatory markers.

The most significant results observed for length of sedentary time were for blood fats and insulin resistance markers.

The oxidative stress and ALS association has however been confirmed in a previous study, significant decreases in markers of inflammation and oxidative damage was demonstrated in rats fed spinach or spirulina supplemented diets.

Although it may be that the IGF1 level is simply a dietary marker rather than a significant causal agent in and of itself.

Markers of bone turnover tended to decrease on the high - protein diet but the decrease was not statistically significant.

There are several studies with generic multivitamins for important quality of life health markers that have shown statistically significant benefit.

One study showed there was no significant difference between the Portfolio diet and «statin» therapy in lowering cholesterol and reducing C - reactive protein (CRP), a marker of inflammation.

Women with knee arthritis who drank tart cherry juice twice a day experienced a significant reduction in inflammatory markers, according to a trial published in the July 2012 issue of the Journal of Food Studies.

While the dose was not high enough to completely reverse the reduced T4 to T3 conversion seen with obesity, there was a significant reduction in a number of cardiovascular risk factors, including cholesterol and markers for insulin resistance.

Hinton found significant increases in markers of bone formation and bone breakdown among the athletes whose energy intake matched their energy expenditure throughout the race.

The results were significant: Levels of several different thyroid antibodies that serve as markers for Hashimoto's dropped between 40 and almost 60 percent!

Significant reductions in blood pressure, insulin resistance, and inflammatory markers (hs - CRP) were shown with the higher dose of soy supplementation.

HPO induced a significant increase in serum markers of liver and kidney damage as well as con - comitant lipid abnormalities and a marked reduction in serum HDL - C.

These patients saw their body mass index (BMI) drop from 31.5 to 27.4, lost significant amounts of belly fat, and saw improvement in several other markers of health (18).

A 2012 study from Diabetes Care, however, found that 24 months of treatment with benfotiamine had no significant effects on peripheral nerve function or markers of inflammation in participants with type 1 diabetes.

There is generally significant loss of belly fat — this is a marker for obesity and is dangerous as it surrounds critical internal organs.

This data suggests a different effect of ketosis on glucose homeostasis in diabetic and non-diabetic individuals.21 Other studies support the long - term efficacy of ketogenic diets in managing complications of T2D.36, 37 Although significant reductions in fat mass often results when individuals restrict carbohydrate, the improvements in glycaemic control, haemoglobin A1c and lipid markers, as well as reduced use or withdrawal of insulin and other medications in many cases, occurs before significant weight loss occurs.

▲ 3Subjects using another core ingredient in Six Star ® Joint & Muscle Recovery experienced a significant decrease in a key marker of muscle damage at 2 and 24 hours post-workout compared to subjects using a placebo.

Since they weren't overweight and didn't have any health condition, it is quite troubling that 14 days of inactivity caused small but significant changes in markers that predispose people to risk.

Subjects using the precise dose of OptiMSM ® in Six Star Joint & Muscle Recovery experienced a significant decrease in a key marker of muscle damage at 2 and 24 hours post-workout compared to subjects using a placebo.

Qing Li and his colleagues from Nippon Medical School found that visits to the forest (compared with urban trips) can have a long - lasting influence on immune system markers, increasing the activity of antiviral cells and intracellular anti-cancer proteins — and these changes remained significant for a full week after the visit.

From the moment I navigated to The Frozen Wilds» first blue exclamation point quest marker, it was clear that developer Guerilla Games had used every hour since the original release to sharpen the experience to a fine point, trimming away everything unnecessary and making significant quality - of - life improvements.

«Then, after about four to five weeks, we'd do a task... and send it to our NAPLAN marker to mark that aspect of the writing to see if we've had significant shift.»

And I think that there have been a number of really significant markers, the most recent being that Amazon just announced last week that it had sold more electronic books than hard covers in the last three months.

When the vets checked immune system markers they found a significant amount of the interferon - inducible Mx protein, a sign of an as - yet unidentified infective or environmental immunogenic trigger for the illness.

In beach side towns many streets are named after the forces who liberated them and there are markers on the sites of many of the most significant battles, such as the cliffs at Pointe du Hoc and the Pegasus Bridge, and off the coast from Arromanches you can still see the remains of the Mulberry harbour, which was the man made temporary harbour dragged from England that enabled a full scale invasion bypassing the heavily fortified ports.