Although the CIs cross zero for incidence of type 2 diabetes mellitus, premenopausal ovarian cancer, and premature deaths, the associated costs are statistically
significant because of the
nonlinear nature of these
relationships.
Finally, to examine possible threshold and
nonlinear relationships that might cut across current overweight and obese cut points, locally weighted regression techniques were used to generate lines of best fit for the
relationships between BMI z scores and PedsQL total, summary, and subscale scores that differed significantly by weight category; P <.05 was considered
significant.