REVEALER is a powerful approach but requires as input high - quality genomic data and
a significant number of cancer samples, which can be a challenge, Tamayo says.
Previous research has shown that
a significant number of these cancer «recurrences» are actually persistent tumors that were missed during the first surgical procedure.
Not exact matches
«A
significant number of advanced prostate
cancer patients treated with a chemical castration therapy called androgen deprivation therapy (ADT) experience relapse with relentless progression to lethal metastatic, castration - resistant prostate cancer,» said Ronald DePinho, M.D., professor of Cancer Bi
cancer patients treated with a chemical castration therapy called androgen deprivation therapy (ADT) experience relapse with relentless progression to lethal metastatic, castration - resistant prostate
cancer,» said Ronald DePinho, M.D., professor of Cancer Bi
cancer,» said Ronald DePinho, M.D., professor
of Cancer Bi
Cancer Biology.
Considering the thousands
of people diagnosed with these
cancers annually, a 1 % increase in early - stage diagnosis could add up to a
significant number of new cases and potentially lead to better outcomes.
«These new results are
significant because they represent the discovery
of a
number of more potent variations
of the natural product as cytotoxic agents against
cancer cells,» Nicolaou said.
Further, a
significant percentage
of these complex mutations are found in well - known
cancer genes that could be targeted by existing drugs, potentially expanding the
number of cancer patients who may benefit.
Other recent studies have recognized HCV's increased association with additional
cancers, says Torres, but there was no known association with a
significant number of head and neck
cancers.
Additionally,
significant numbers of diagnosed prostate
cancers are
of low grade and will not cause symptoms or disease - specific mortality.
«The benefits
of early therapy are
significant, since it increases the
number of healthy life years for patients and decreases their chances
of getting serious liver diseases, like liver failure and liver
cancer,» said Harinder Chahal, PharmD, MSc, an assistant adjunct professor in the UCSF department
of clinical pharmacy.
«It is not mutated in every type
of cancer, but in a
significant number.
The Comer Kids» Classic grant enabled Henderson to improve the care
of all childhood
cancer survivors, including a
significant number of minority
cancer survivors who had been underrepresented in the past.
Many
of these novel
cancer immunotherapy approaches, which originated from basic science research in CCIR laboratories, are now being explored as new treatment modalities in patients, with a
significant number advancing through clinical trials towards FDA approval.
The implant allows you to track changes in the level
of calcium and notify your carrier.Swiss scientists at ETH Zurich have developed a tattoo that tells its owner about the disease
cancer in its early stages.It is known that in a
significant number of...
While much recent research has not been published in this area, there is actually a long history
of studies that show: (1) there is a
significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against
cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against
cancer can be generated by vaccinating animals with embryonic tissues.
Compared with ever - users
of other types
of antihypertensive medications, users
of short - acting CCBs had a hazard ratio (HR) for development
of pancreatic
cancer of 1.66, which was
significant after adjustment for a
number of relevant factors.
All
of the
significant regions had been previously reported / validated; they included or were proximal to a
number of well - known
cancer genes including EGFR, CCND1, KRAS, MDM2, PDGFRA, and others.
«The
cancer care and research community at MSM has seen
significant growth over the past five years; doubling the
number of oncologists and quadrupling the amount
of translational research funding.
Because
of small sample size, the changes in tumor - initiating cell
number were not
significant (P > 0.05), but these data are supportive
of the in vitro findings and suggest that hypoxia may have a positive effect on the tumor - initiating cell population in ER - α — positive breast
cancers and a negative effect in ER - α — negative tumors.
Although these
numbers seem small, they have a
significant impact on dogs, since this form
of cancer kills.
Despite this, a
significant number of studies revealed that parents underestimated the impact that their
cancer had on their children.