Sentences with phrase «significant phase in»

2018 marks the next significant phase in the Gallery's history.

«The launch of our first golf course adds another dimension to Jordan's tourism offering and marks a significant phase in increasing the profile of Aqaba with British tourists.»

THE END of the wet in the Kimberley region has signalled the start of a most significant phase in the resurgence of diamond exploration in WA's far north.

Not exact matches

One «experiment» would be to communicate to all clients that there is going to be a phased move to a paperless office because it; meets legal requirements, documents are more secure and accessible in the cloud, it saves significant costs, and is better for the environment.

Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).

The project would employ a significant number of temporary construction workers during the building phase, though pipelines generally do not require much labor to operate in the long term.

If we do observe significant fresh credit strains, our valuation criteria will be more demanding, particularly in the initial recognition phase.

The Fund invests mainly in mid-sized U.S. companies that have matured beyond their start - up phase and have significant secular growth opportunities.

Given the significant expansions in capacity in the resource sector over recent years, and the lag between investment and the corresponding output, the production phase of the resource boom is expected to gather momentum over the next couple of years.

Even before the price rises for oil and other commodities seen this year, Australia had experienced a significant pick - up in inflation, in the mature phase of a long period of economic expansion.

McGovern qualifies Sigmund's two - phase presentation in significant ways.

And now we must turn to the critical phase of this paper wherein I shall designate the points at which I find myself in tension with the theological proposals of this highly significant work, Christ Without Myth.

On the contrary, the new agroforestry criterion 2.5 will be mandatory for all certified farms after a phase - in period of three years and will ask for a significant portion of trees and natural vegetation on farms with the aim to stabilize the agro-ecosystem and increase the environmental services provided on certified farms.

«Her skills and experience will be critical as financial services moves from an era of the most significant changes in regulation and legislation in its history to its next phase of being an export and growth industry for Australia,» FSC chairman Greg Cooper said.

A significant window in the Transformation phase.

In the US, the pilot phase of an outstanding multi-site intervention which aims to equip low income couples with relationship / communication skills is reporting significant positive results.

Remember, your child may go through phases when he is more in need of your attention and love, especially during times of significant stress or tragedy.

The trip marks a new phase in the nine - month tenure of the former federal prosecutor who won a solid victory over incumbent Democratic Gov. Jon Corzine in November 2009, a victory that presaged a significant change in GOP fortunes.

Ossining for Fair Funding Communications Director Jessica Vecchiarelli said: «With significant enrollment growth and substantial increases in student needs, we are simply asking that Ossining be put on a path to being funded at the same percentage level as the average district in New York State, at least 80 % of the fully phased - in Foundation Aid.

The state's Restaurant Owners Association, in a statement, says «any substantial raise to wages needs to be phased in over a significant amount of time» in order to give allow restaurants time to prepare for what they say will be a «huge increase in labor costs.»

In addition the Panel on Educational Policy must approve any shutdown, phasing out or significant change in the use of a school buildinIn addition the Panel on Educational Policy must approve any shutdown, phasing out or significant change in the use of a school buildinin the use of a school building.

«We are pleased that our lawmakers are enacting significant new tax cuts for the seventh consecutive year, with a cumulative total effect, when fully phased in, of some $ 13 billion,» said Business Council President Daniel B. Walsh.

In this way, it was possible to prove experimentally for the first time that it is not just the electrons which play a significant role in the phase transition but also the atomic lattice — the solid's scaffolIn this way, it was possible to prove experimentally for the first time that it is not just the electrons which play a significant role in the phase transition but also the atomic lattice — the solid's scaffolin the phase transition but also the atomic lattice — the solid's scaffold.

«It seems that the sun's quiescence was responsible for the most extreme phases of the Little Ice Age, implying that solar variability sometimes plays a significant role in climate change.

Our study is significant because, while there are various different estimates for the start and end of the Little Ice Age in different regions of the world, our data show that the most extreme phases occurred at the same time in both the Northern and Southern Hemispheres.

«The results of the phase III clinical trial show that a target fusion biopsy detects more clinically significant prostate cancer,» said Art Rastinehad, DO, principal investigator of the study and director of interventonal urologic oncology at North Shore - LIJ's Arthur Smith Institute for Urology, in New Hyde Park, NY.

These statistically significant and clinically meaningful improvements in overall response and survival rates resulted from a phase Ib / II clinical study performed at the HonorHealth Research Institute, a partnership of HonorHealth and TGen.

Researchers at Tohoku University's Advanced Institute for Materials Research (AIMR) have carried out a collaborative study aimed at precisely controlling phase transformations with high spatial precision, which represents a significant step forward in realizing new functionalities in confined dimensions.

«There is a significant possibility that local therapy, such as consolidative radiation, may become an important part of the management of limited metastatic NSCLC patients, but this validation must take place in randomized phase III studies.

«However, as immunosuppression drugs required for transplantation can have significant adverse side effects, the treatment only makes sense for people who have frequent severe hypoglycemia despite optimal diabetes management, or for those already on immunosuppressant drugs for a kidney transplant, a group being studied in another Phase 3 trial.»

«We look for activity of our molecules in phase 2, and on numerous occasions we generate statistically significant data with relatively small numbers of patients, which gives us reasonable confidence that the program will be successful in phase 3 with a larger group of patients.

In phase 3 trials for adults with high - risk, secondary AML, there was a statistically significant improvement in overall survival compared to patients who received a regimen using chemotherapy drugs delivered in the standard waIn phase 3 trials for adults with high - risk, secondary AML, there was a statistically significant improvement in overall survival compared to patients who received a regimen using chemotherapy drugs delivered in the standard wain overall survival compared to patients who received a regimen using chemotherapy drugs delivered in the standard wain the standard way.

Scientists have debated whether the first significant phase of the compilation of biblical texts happened before or after the fall of the first Temple, in 586 B.C. To get at the potential answers to that question, a group of researchers in Israel analyzed mundane inscriptions about the needs of daily life on 16 ceramic shards written about 600 B.C. from an ancient military fortress in Arad, at the northern edge of the Negev desert.

Between - group analysis of phase 2 demonstrated a significant activation cluster in the ipsilateral posterior insula (pIns) in group P. Using the pIns as a seed region the PPI analysis yielded a significant enhanced coupling to the midbrain (periaqueductal grey / ventral tegmental area) after analgesia onset in group A only.

The U.K. contribution constitutes a significant portion of the $ 650 million first phase of construction, which will begin in 2018.

This information was critical in the design and implementation of the current Phase 1 trial and will be of significant benefit in planning the Phase 2/3 clinical efficacy trial.»

«You can build up significant quantities of water in the gas phase even without much enrichment in heavy elements,» adds Bialy.

The researchers found that timing — specifically, the phase of the cell division cycle that bacteria were in when exposed to the antibiotic — had a significant effect on susceptibility.

«Regorafenib shows significant survival gains in refractory liver cancer: Phase III trial confirms efficacy and safety of new second - line agent.»

In the nonstimulation trials, there was no significant change in theta - phase resetting after the trial onseIn the nonstimulation trials, there was no significant change in theta - phase resetting after the trial onsein theta - phase resetting after the trial onset.

It remains the fastest growing component of the widening gap between the Ecological Footprint and the planet's biocapacity,» Wackernagel said adding that a global agreement that aims to phase out fossil fuels could have a significant impact in helping curb the consistent growth and even shrink Ecological Footprint, humanity's demand on planet Earth.

«NASA required we successfully complete the Certification Baseline Review — our first CCtCap (Commercial Crew Transportation Capability Phase) milestone, successfully complete an interim milestone representing work culminating in a significant design review (for us, this was the Delta Integrated CDR (Critical Design Review), our 4th tCap milestone), and meet additional ATP criteria we proposed (that is different for each provider),» Boeing's Kelly Kaplan told SpaceFlight Insider.

Together these data will support future efforts to conduct Phase I clinical trials in humans and constitute significant progress on the pathway toward a vaccine for falciparum malaria.

No significant correlation was observed between Cyclin D1 staining and S - phase % obtained by flow cytometry as illustrated in Table 5.

We found coherent and significant SPI [standardized precipitation index] responses to ENSO phases in most of the seven regions considered

In summary, our results point to both a significant «vacation effect» that benefitted all groups, and a suppression of stress - related responses and immune function related to acute - phase wound healing and inflammation.

Patients with chronic myeloid leukemia in the blast phase pose a significant therapeutic challenge and have poor survival, even in the tyrosine kinase inhibitor era, according to a new study.

In the IMPC phase 2 a significant fraction of mutant lines will be aged and re-phenotyped to identify genes involved with late - onset disease.

Soft Tissue Sarcoma Opportunity: in both our monotherapy single arm Phase 1 and combination randomized Phase 2 studies, we are focusing on two types of sarcoma where we believe there is significant unmet need: synovial sarcoma and Myxoid round cell liposarcoma.

In our first study, we observed a significant improvement in both the acquisition and reversal phases of the task in mice treated with 0.6 mg / kg donepeziIn our first study, we observed a significant improvement in both the acquisition and reversal phases of the task in mice treated with 0.6 mg / kg donepeziin both the acquisition and reversal phases of the task in mice treated with 0.6 mg / kg donepeziin mice treated with 0.6 mg / kg donepezil.