Sentences with phrase «significantly altered genes»

For this compilation, I've emphasized publications in which whole - genome or exome sequencing was employed to multiple tumors or cancer cell lines, with the goal of identifying significantly altered genes or pathways in malignant cells.

Not exact matches

As in any good marriage, moreover, the attachment of the methyl groups significantly altered the behavior of whichever gene they wed, inhibiting its transcription, much like a jealous spouse.

Animals with gene mutations that significantly alter their circadian rhythms have shorter life spans, and circadian rhythm sleep disorders in humans can have profoundly negative effects, including increased risk for obesity, depression, cardiovascular disease and cancer.

From a more global perspective, 22 gene families, of the over 200 identified, were found to be significantly altered by hypoxia.

Miller, C.J., Kassem H.S., Pepper S.D., Hey Y., Ward T.H., Margison G.P. «Mycoplasma infection significantly alters microarray gene expression profiles.»

Polymorphisms in five of 15 genes (33 %) encoding molecules known to primarily influence pancreatic beta - cell function - ABCC8 (sulphonylurea receptor), KCNJ11 (KIR6.2), SLC2A2 (GLUT2), HNF4A (HNF4alpha), and INS (insulin)- significantly altered disease risk, and in three genes, the risk allele, haplotype, or both had a biologically consistent effect on a relevant physiological trait in the QT study.

In fact, a study in Child Development revealed that when parents are significantly stressed during their child's first few years of life, some of the child's genes can even be altered, harming development and leading to negative effects years later.

When parents are significantly stressed during their child's first few years of life, some of the child's genes can be altered.