Sentences with phrase «significantly decreased expression»

We found that 180 genes showed significantly decreased expression and 40 genes showed significantly increased expression in ABL1 / ABL2 knockdown cells (fig.

Not exact matches

When they also looked for human genes with significantly higher or lower expression levels, they found 14 genes with increased expression and five with decreased expression.

In the AD mice, the expression of ERK1 / 2 was significantly increased (p < 0.05), while the level of BDNF was decreased (p < 0.05).

Silencing of Nrf2 significantly decreased baseline levels of HMOX1, whereas silencing of Bach1 resulted in a 50-fold increase in expression of HMOX1 mRNA (Figure 4B).

Using both semi-quantitative-reverse transcriptase PCR and Quantitative Real - Time PCR to assess the resulting levels of sema2a expression, we confirmed that our method of RNAi significantly decreased sema2a levels (Figure 1A - B).

ActD - induced p53 - expression significantly decreased when AKT expression was knocked - down by shRNA.

When AKT was downregulated by small hairpin RNA - AKTs, ActD - induced p53 expression was significantly decreased.

Transgene suppression over 2,5 months is decreasing tau expression significantly, resultíng in normalization of T - maze performance, but also modulation of practically all disturbed behavioral features that were investigated using Smart Cube, Neuro Cube and Pheno Cube, including motor function, rearing, hyperactivity and social behavior.

The minor allele of rs25532 significantly decreased luciferase reporter gene expression levels by 15 — 80 %, depending on 5 - HTTLPR allele background and cell type.