Sentences with phrase «significantly higher expression»

Among the receptors, expression of mRNA of genes that encode for NTRK2, NGFRAP1, ESR1 and EDNRA was higher in cumulus cells, while oocytes had significantly higher expression of mRNA of genes that encode for IGF1R, ESR2 and TGF - βR3.

Interestingly, although larvae fed on either linseed oil or sucrose showed significantly higher expression of gbp1 and gbp2 when compared to those fed on agar, the effects on up - regulating gbp1 and gbp2 expression were significantly lower than that of casein.

ELOVL6 and GYS2 had significantly lower expression, and SPP1 and IL1RN had significantly higher expression in obese versus nonobese NGT subjects (Fig. 1E).

Not exact matches

Furthermore, the levels of Runx2 expression among a larger group of 351 newly diagnosed multiple myeloma patients were significantly higher in patients who had a high risk of early disease - related death, as compared with lower - risk patients.

«Differential expression» means the microRNA, or miRNA, expression could be higher or lower in the different conditions, but it's the fact that they are significantly different that makes them of interest and potential help in better understanding and treating a leading cause of vision loss worldwide, Liu says.

«We found that the incidence of EMD was significantly higher in patients with high expression of AF1q than those with low expression,» Tse said.

Mesenchymal glioma stem cells show significantly higher radiation resistance and high expression of DNA - repair genes;

They found that STAT3 core signature was significantly enriched in AML cases with high PRL - 3 expression.

Unlike most biomarkers for cancer, DDX3 mRNA expression only increased slightly in the exposed breast cells, but the corresponding proteins levels were significantly higher.

Interestingly, high expression of KLF4 was significantly and inversely correlated to brain but not bone metastasis - free survival of patients with breast cancer, and we indeed found that the expression of miR - 7 significantly suppressed the ability of CSCs to metastasize to brain but not to bone in our animal model.

We found that the expression of miR - 7 was significantly lower in brain metastatic tumors than that in primary tumor tissues (Fig. 6A, left), whereas the expression of KLF4 was significantly higher in brain metastatic tissue compared with primary tumors (Fig. 6A, right).

Expression was significantly higher in metastatic versus primary tissue cores (P < 0.05), as shown in Figure 2.

Unpaired t tests showed that PD - L1 expression was significantly higher in metastatic versus primary tissue cores.

Among the growth factors, expression of mRNA of genes that encode for GDNF, FGF2, GM - CSF and TGF - β1 was significantly higher in cumulus cells than in oocytes.

When they also looked for human genes with significantly higher or lower expression levels, they found 14 genes with increased expression and five with decreased expression.

Dr Gilchrist said: «This study suggests that we may improve significantly on the widely used analysis methods for determining gene expression levels from high throughput sequence data: absolute quantitation offers a much sounder basis for determining changes in gene expression level, a measure widely used to determine the consequence of genetic, chemical or physical disturbances in living systems.»

However, when we extracted gene expression levels from the brain transcriptome data following the methodology in Carneiro et al. [29], we found that levels of nucleotide diversity and the proportion of low frequency variants between lowly (bottom 5 %) and highly (top 5 %) expressed genes in our dataset (Table S7) were not significantly different in most comparisons (with the exception of π in O. c. cuniculus) nor did they consistently differ in the expected direction when assuming higher error rates in lowly expressed genes.

Of the two telomerase components analyzed, Tert (telomerase reverse transcriptase) expression did not show any differences between groups, but Terc (telomerase RNA component) transcription was significantly higher in the IVC testes (Fig. 2B).

Comparison of gene expression profiles indicate that both the SLC2A1 and CLICl receptor subunit transcripts are expressed at significantly higher levels in NSCs but not in differentiated neurons, suggesting that NSCs may be more sensitive to the channel - effects of amiodarone HCL.

Examining expression levels of H2AX in breast cancer tumor data from The Cancer Genome Atlas, a large National Institutes of Health database containing genetic information about tumor tissue from more than 11,000 patients, the Roswell Park team found that breast cancer patients whose tumors had high levels of H2AX had a significantly worse prognosis than those with low levels.

(A) MELK expression levels are significantly higher in breast carcinoma (n = 392, red circles) than in normal breast tissues (n = 61, blue circles) in the TCGA breast cancer cohort (Cancer Genome Atlas Network, 2012).

The results show that eHarmony couples scored significantly higher in regard to all four components of relationship quality measured by the Dyadic Adjustment Scale (DAS): consensus, satisfaction, affectional expression and cohesion.

This puts the Cullinan at a significantly higher price point than the Bentayga, but as an expression of the ultimate luxury SUV, few, if any will likely be able to match it.

We found that levels of physical aggression were significantly higher in men who had experienced traumatic events during the first 15 years of life and who carried the low expression allele (MAOA - L).

Independent observations of children's behavior found that treatment group children showed significantly fewer submissive behaviors (e.g., approval - seeking or help - seeking) and negative behaviors (e.g., pouting, ridicule) and higher rates of positive - affect behaviors (e.g., smiling, expressions of affection) than control group children.

Outside the relationship, depression is significantly associated with higher rumination, problem - solving and emotional expression in depressed women and with higher avoidance in depressed men (e.g. Bodenmann et al., 2004).