Sentences with phrase «significantly inhibits»

Hourly billing, and even flat - fee billing that is based on the estimated hours required, is not scalable and significantly inhibits your growth potential.

Studies show exposure to light after dusk, particularly light from computer screens, iPads, iPhones, televisions, and other electronic items, significantly inhibits the production of melatonin, your body's sleep hormone.

It significantly inhibits serum creatine kinase activity and incidences of ventricular tachycardia.

The study concluded that krill oil at a daily dose of 300 mg significantly inhibits inflammation and reduces arthritic symptoms in as little as seven to 14 days!

Plant Food Delphinidin -3-Glucoside Significantly Inhibits Platelet Activation and Thrombosis: Novel Protective Roles against Cardiovascular Diseases.

In our study, pentobarbital inhibited 5 - HT evoked calcium signals in geniculate ganglion neurons and, at anesthetic levels in mice, significantly inhibits 5 - HT3 function in vivo.

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco - derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research (AACR) Annual Meeting in New Orleans.

Casein, on the other hand, increases protein synthesis like whey, but also significantly inhibits protein breakdown.

Green Tea Ingredient, EGCG, Significantly Inhibits Breast Cancer Growth In Female Mice.

Living my teens and early twenties with breasts that were disproportionately large for my body significantly inhibited my ability to exercise and find appropriate clothing, caused back pain, and impacted hugely on my self - confidence.

«We also confirmed a role in PDAC tumor maintenance as inhibition of PRMT1 in patient - derived mouse models significantly inhibited tumor growth and extended survival,» said Giuliani.

«If you don't significantly inhibit the replication, you can end up getting a lot of resistant virus.»

The compound then was tested in an experimental model for melanoma and found to significantly inhibit tumor cell growth without appreciable toxicities.

Bacteria exposed to it either fused into long chains or exploded, significantly inhibiting growth of the culture.

«Even when we administered Del - 1 after the peak recruitment of neutrophils, we were still able to significantly inhibit bone loss,» Hajishengallis said.

«Our data confirmed that, while the rate of growth of triple - negative breast cancer was not affected by CDK 4/6 inhibitors, this class of drugs was able to significantly inhibit the spread of triple - negative breast cancer to distant organs when tested in multiple different triple - negative breast cancer models, including patient - derived xenografts.»

All six significantly inhibited growth of the fungus, and two isolates performed especially well in suppressing fungal growth for more than 35 days.

They will follow this approach to design a novel treatment plan by rationally combining gemcitabine with cell cycle checkpoint inhibitor, oxygen - enrich gas inhalation, and radiotherapy to significantly inhibit the growth of aggressive glioma.

Additional experiments showed that genetic disruption of MrcA, depletion of ITPR3, and depletion of STIM1 all significantly inhibited extrusion in infected cells, as did chemical disruption of calcium ion signaling.

They also investigated a new strategy to significantly inhibit glioma growth by rationally combining gemcitabine and MK - 8776, a cell cycle checkpoint inhibitor.

Also, the research showed that this localised delivery of combination therapy significantly inhibited the recurrence of cancer after a primary tumour was surgically removed.

The benzamidazole mebendazole significantly inhibited growth of adrenocortical carcinoma cells, both in vitro and in vivo, the effects being due to induction of apoptosis [19].

Subsequently, numerous compounds have been shown to significantly inhibit CXCR4.

Furthermore, the effects of the neonicotinoids were significantly inhibited by the nAChR antagonists mecamylamine, α - bungarotoxin, and dihydro - β - erythroidine.

Moreover, we found that IRF - 9 could significantly inhibit the transactivity of IRF - 1 in a dose - dependent manner (Fig. 5A), reflecting again their competition for direct binding with RIG - G promoter.

Regorafenib, a recently characterized RIPK2 inhibitor, did not significantly inhibit the proliferation of these cells in an MTT assay (3 -(4,5 - dimethylthiazol -2-Yl)-2,5-diphenyltetrazolium bromide)(Fig. 6A).

Using this treatment scheme, we observed a robust difference on day 9 in the disease activity indices of wild - type and Rassf1a knockout mice that was significantly inhibited with the use of the RIPK2 inhibitors, especially RIPK2 inhibitor 1 (Fig. 6B; Table 2).

A follow - up study showed that ApoC - III did not significantly inhibit ApoE - mediated VLDL binding to LRP1 (36).

According to a study, the proliferation of cancer cells of the esophagus can be significantly inhibited with zinc supplementation.

Specifically, they found that berberine significantly inhibited amyloid beta - stimulated production of several inflammation markers, including interleukin - 6 and monocyte chemotactic protein - 1.

Changes in the thiol / disulfide redox status (discussed in Part II of this review in relation to the connections among homocysteine, methylation and transsulfuration) can also significantly inhibit the activity of the redox - sensitive phosphatases that regulate insulin signaling.

STUDY ONE — this study found that an extract of purple sweet potatoes fed to rats with liver damage significantly inhibited COX - 2.

In a recent study published in Journal of Agricultural and Food Chemistry, researchers noted that bilberries significantly inhibited angiotensin - converting enzyme, which narrows the arteries and contributes to high blood pressure.

STUDY SEVEN — cysteine, histidine and glycine all significantly inhibited NF - KappaB, a master molecule that activates the release of many pro-inflammatory chemicals behind acne.

A 2010 scientific study published in the Journal of Experimental Biology and Medicine tested and analyzes five species of mushrooms (maitake, crimini, portabella, oyster and white button) and it was discovered that they significantly inhibit proliferation of breast cancer cells, suggesting mushrooms may be chemoprotective against breast cancer (3).

In turn, IL - 4 may significantly inhibit the production of TNF by monocytes (Hart et al. 1989), which reinforces the potential role of adequate zinc status in preventing disease progression in HIV - 1 infection (Rosenberg and Fauci 1990).

Postprandial increases in both blood glucose and blood insulin were significantly inhibited in subjects in the borderline group who took the test food in comparison with the placebo group (blood glucose: p < 0.05 and p < 0.01 at 1 and 1.5 h after ingestion respectively; insulin: p < 0.05, p < 0.01 and p < 0.05 at 1, 1.5, and 2 h after ingestion respectively).

The first of these HAB - supported studies was published in November, 2012.1 The small UCLA - led pilot study found that eating one - half of a fresh medium Hass avocado with a hamburger (made with 90 percent lean beef) significantly inhibited the production of the inflammatory compound Interleukin - 6 (IL - 6), compared to eating a burger without fresh avocado.

«In our current study, we found that resveratrol can remodel the gut microbiota including increasing the Bacteroidetes - to - Firmicutes ratios, significantly inhibiting the growth of Prevotella, and increasing the relative abundance of Bacteroides, Lactobacillus, Bifidobacterium, and Akkermansia in mice,» said Dr. Mi.

If there is not enough, the child's development may be significantly inhibited.

Not exact matches

The report's author, Dr Leslie Budd from the Open University, argued that as well as damaging Northern Ireland's attractiveness as an entry route into the single market, transaction costs for trading into the EU would «rise significantly» and inhibit economic co-operation with the neighbouring Irish Republic.

Furthermore, they found that by inhibiting Akt they could significantly slow cell proliferation, cell migration and cell invasion in the lung cancer and bladder cancer cells.

As in any good marriage, moreover, the attachment of the methyl groups significantly altered the behavior of whichever gene they wed, inhibiting its transcription, much like a jealous spouse.

With this new understanding of how Del - 1 can inhibit periodontal bone loss — both by reducing inflammation and by restraining the activity of osteoclasts that resorb bone tissue — the researchers tested it, in a preclinical model of periodontitis observing that Del - 1 significantly reduced inflammation and tissue damage and that there was significantly less bone loss.

Inhibiting HMGB1 dramatically reduced malignant mesothelioma growth in mice and significantly improved survival of treated animals,» said Dr. Haining Yang, PhD, an associate professor in the Thoracic Oncology Program at the UH Cancer Center.

This study shows that inhibiting PRMT5 can significantly improve survival in an animal model of GBM.

Toon notes that impacts on land or shallow water may ultimately do more damage by kicking up dust that could significantly darken skies and inhibit plant growth.

The scientists found that application of dicamba inhibited or delayed flowering in common boneset (Eupatorium perfoliatum), resulting in significantly reduced visitation by insect species, including honeybees (pollinators) and syrphid flies (natural enemies).

However, when the D1 receptor was inhibited, alcohol - seeking behavior in individuals with stroke damage decreased significantly while the control group didn't exhibit much of a change.

She also noted the targeting Msi in primary tumors significantly changed «the trajectory of progression by halting pancreatic cancer growth and improving survival,» inhibiting both cancer stem cells and other tumor cells.