Not exact matches
The brains
of people with Alzheimer's show several
signs of the disease:
plaques made
of a protein called
amyloid - β, tangles
of a protein called tau and the loss
of neurons.
Scientists have long considered clumps
of amyloid plaques — sticky, barnacle - like protein bundles — to be the first
sign of Alzheimer's.
AMYLOID plaques are a
sign of Alzheimer's disease, and bad news for humans.
Two participants had remarkably clean brains with few
signs of amyloid - beta
plaques and tangles
of tau protein.
That agent, aducanumab, is designed to bind preferentially to the early clumps
of amyloid as they form
plaques, and therefore may be more useful in mild or moderate patients who are already showing
signs of memory loss and other cognitive problems.