When mice were given a daily saccharin solution for 28 consecutive days, morphine no longer resulted in any amount of the typical analgesia.17 In other words, the tolerance of opioids in the mice was increased from the sweet taste of saccharine, necessitating larger doses of opioid drugs to achieve
similar analgesic effects.
Not exact matches
The scientists discovered that a class of mechanoreceptors in the skin that detect painful mechanical stimuli are part of a feedback circuit in which excitatory neurons that produce the hormone somatostatin are inhibited by neurons that synthesize dynorphin (a natural
analgesic molecule that produces
effects similar to opiates).
People need to simply remember that herbs are medicines and that an herb with actions
similar to prescription sleep aids and
analgesics will of course pack the same side
effects.