A recent study showed exposure flu viruses among women during pregnancy provoke
a similar gene expression pattern in the fetus as that seen in autistic children.
Comparison of the transcripts revealed that breast cancer cells with knockdown of ABL2 alone shared
a similar gene expression pattern with that of the ABL1 / ABL2 double - knockdown cells (Fig. 6A and fig.
Not exact matches
By day 34 of development, however, the
pattern of
gene expression was much more
similar to control cows derived from artificial insemination, suggesting that these surviving clones were able to implant in the uterus and begin to form a placenta.
SIX3 and a related
gene, SIX2, with a
similar pattern of
expression in human beta cells, encode proteins known as transcription factors that control the
expression of many other
genes in the cell.
Surprisingly, they found that although the
patterns of
gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall
pattern of mutations in the cells was actually
similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.
The
gene expression patterns were so
similar, in fact, that investigators were able to use them to match up the stages in worm and fly development.
Rather than listing specific
genes that manifest themselves differently, or are differentially expressed, between queens and workers, the team looked for
genes with
similar expression patterns across samples that may be involved in maintaining the structural, behavioural and functional differences observed between queens and workers.
The
pattern of
gene expression is strikingly
similar to that for individual olfactory receptor
genes, Liberles says.
Humans have an ortholog of the murine Nrk
gene, and considering that the
gene expression pattern in breast tumor in Nrk mutant mice was
similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.
A further 25 days in medium containing FGF2 and Noggin mediated the derivation and expansion of RPCs which had a
similar global
gene expression pattern to cells of the embryonic day 14 (E14) mouse retina.
A detailed comparison of
gene expression signatures between ETP ALL tumors and and normal human hematopoietic progenitor cells revealed a somewhat surprising finding: ETP - ALL
expression patterns were less consistent with early T - cell precursors, as might have been expected, but more
similar to the
expression profile of normal hematopoietic stem cells and granulocyte macrophage precursors.
«What we found is that the majority of the
gene expression patterns are very
similar in human and mouse,» Yue said.
Click «
Expression Details» to view all expression annotations and details for this locus, including a visualization of genes that share a similar expressio
Expression Details» to view all
expression annotations and details for this locus, including a visualization of genes that share a similar expressio
expression annotations and details for this locus, including a visualization of
genes that share a
similar expressionexpression pattern.
«After feeling comfortable with the accuracy of the statistical model, we can scale up to search among thousands of
genes to discover those with
similar expression patterns.»
CT values for cyclophilin were somewhat more variable in cells isolated by flow cytometry and frozen prior to analysis, compared to freshly isolated and unmanipulated cells, but the gradients in
patterns of
gene expression were
similar for cells isolated by the two techniques (Figure 3a — d).