Sentences with phrase «similar gene in humans»

Researchers have discovered a gene in zebrafish so powerful it can be used to redirect the fate of cells in the developing embryo to become beating heart cells, suggesting that a similar gene in humans could be used to generate heart cells in culture for transplant in ailing people.

Not exact matches

Similar mechanisms are found in human brains — caregiver behavior matters for turning genes on and off.

The human genome contains some 20,000 - 25,000 protein - coding genes, which is surprisingly similar to the number of genes in worms and flies.

But look much closer, at a genetic level, and you will find that many of the genes seen in these flies are also present — and play similar roles — in humans.

Carlo Croce, a cancer researcher at Ohio State University in Columbus, and his colleagues created a diagram of interacting miRNAs for normal body cells by connecting them according to which genes they target and the function of those genes, in a way similar to analyses of human social networks.

The researchers also found that four of the affected genes in the hippocampus and one in leukocytes are similar to genes in humans that are linked to PTSD.

Mice without the leptin gene, called ob / ob, overeat, weigh in at three to four times normal, and develop symptoms similar to the obesity - related diabetes seen in humans.

They found methylation defects on several human genes in the cord blood and placentas of ART embryos, suggesting that a similar effect might be occurring in humans as well.

Lindstrom and his colleagues inserted genes for human nicotinic receptors into frog eggs and incubated them with levels of nicotine similar to those found in the blood of a human smoker.

Global gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.

SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.

In the case of CHD2, scientists collaborating with the EuroEPINOMICS RES consortium used antisense technology to rapidly generate zebrafish larvae with a partial loss of function of this gene, and were then able to detect epileptic seizures in these animals using electrographic analysis (this method is very similar to electroencephalography, or EEG, which is used to analyze seizures in humansIn the case of CHD2, scientists collaborating with the EuroEPINOMICS RES consortium used antisense technology to rapidly generate zebrafish larvae with a partial loss of function of this gene, and were then able to detect epileptic seizures in these animals using electrographic analysis (this method is very similar to electroencephalography, or EEG, which is used to analyze seizures in humansin these animals using electrographic analysis (this method is very similar to electroencephalography, or EEG, which is used to analyze seizures in humansin humans).

FOLD IT A gene that only humans have can make the normally smooth outer layer of mouse brains develop folds similar to those in human brains (upper right center).

Dr Nadeau added «Our results are even more surprising because the cortex gene was previously thought to only be involved in producing egg cells in female insects, and is very similar to a gene that controls cell division in everything from yeast to humans.»

In a report that appears in PLOS BIOLOGY, Dr. Hugo Bellen and his colleagues at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and BCM, and Dr. Chao Tong, at the Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University in Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neuronIn a report that appears in PLOS BIOLOGY, Dr. Hugo Bellen and his colleagues at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and BCM, and Dr. Chao Tong, at the Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University in Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neuronin PLOS BIOLOGY, Dr. Hugo Bellen and his colleagues at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and BCM, and Dr. Chao Tong, at the Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University in Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neuronin Hangzhou, China, find that mutations of human homologs (genes that carry out similar functions) of cacophony and its partner straightjacket (Cacna1a and Cacna2d2 respectively) cause defects in autophagy in neuronin autophagy in neuronin neurons.

Although that marker, called IL21, had not previously been associated with autoimmune diseases, the gene that produces it sits right in the stretch of DNA known to make these mice vulnerable to diabetes, suggesting that IL21 might make a drug target, says Sarvetnick.Furthermore, by giving the animals a shot of dead bacteria — similar to an immunization in humans — when they were newborns, Sarvetnick and her colleagues prevented a surfeit of CD4 + and CD8 + cells.

ET: «What this data analysis pipeline, moreover, creates is motivation to look for similar forms of gene loss in other types of symbioses, such as that between humans and their gut microbiomes.

The neural circuits underlying social behavior «must be very different for humans and honey bees, yet it appears at the molecular level, the genes are employed in a similar manner,» he says.

Two groups of researchers report today that washing human skin cells in similar cocktails of four genes enabled them to reprogram the cells to resemble those harvested from embryos.

To prevent this decline in Area X, White's research team used methods similar to human gene therapy to insert a version of FoxP2 in male zebra finches.

A human gene similar to the one found in worms may also be involved in our decision - making.

Hebrok found that when the Brg1 gene is knocked out in mice that are predisposed to PanIN development and subsequent PDA, lesions form that are similar to human IPMN.

Further studies showed that very similar genes controlled the process in animal and human cells, and also helped piece together how the genes work together to keep the cell's recycling centers running.

Blau's group found that the daily changes in Rho1 activity are controlled by rhythms in transcription of a gene very similar to human Puratrophin - 1.

The team used gene expression profiling and found that canine B - cell lymphoma expression profiles were similar in many ways to human B - cell lymphoma, thus paving the way for future studies, including therapeutic clinical trials in dogs and humans.

On the other hand, in no case did Africans and Neanderthals share similar versions of a gene, to the exclusion of other humans.

In humans, a similar protein complex called CSN and its subunit CSN6 is now believed to be a cancer - causing gene that impacts activity of another gene (Myc) tied to tumor growth.

This in turn should help geneticists work out the functions of human genes, many of which are likely to have sequences similar to those found in the nematode.

It uses a virus already approved by the Food & Drug Administration for other genetic therapies in the eye; it delivers an ion channel gene similar to one normally found in humans, unlike others that employ genes from other species; and it can easily be reversed or adjusted by supplying new chemical photoswitches.

The paper published online this month in Genetics examines a «foraging gene» humans share in common with the flies, which plays multiple roles and is found in similar places, such as the nervous system, in the muscle and in fat.

A 7000 - year - old hunter - gatherer found in a Spanish cave has a genome surprisingly similar to modern humans, with blue eyes and a host of immunity genes

Indeed, a close look at the chimp genome reveals an important lesson in how genes and evolution work, and it suggests that chimps and humans are a lot more similar than even a neurobiologist might think.

In the study, the scientists used a type of mouse, called CVN - AD, that they had created several years ago by swapping out a handful of important genes to make the animal's immune system more similar to a human's.

The measurement data prove that the feature is inherited in a similar way in all primates — humans included — and varies across different species and genera in a way that mirrors the evolutionary relationships worked out earlier by analyzing bones and comparing genes.

What is remarkable is that the basic organisation of the EDC genes is similar in humans and turtles.

They also showed that certain genes and elements are similar in both species, providing a basis to use the mouse to study relevant human disease.

Because many rabbit genes are similar to their human counterparts, manipulating disease genes in rabbits, like the one responsible for cystic fibrosis, may permit researchers to track the disease's onset and better understand what goes awry.

In human trials, researchers remove some of patients» T cells through a process similar to dialysis and then engineer them in a laboratory to add the gene for the CAR so that the new receptor is expressed in the T cellIn human trials, researchers remove some of patients» T cells through a process similar to dialysis and then engineer them in a laboratory to add the gene for the CAR so that the new receptor is expressed in the T cellin a laboratory to add the gene for the CAR so that the new receptor is expressed in the T cellin the T cells.

Cebrià highlights that «as there are genes which are similar to egr - 4 in other lineages — for instance the human species — , this function may be particularly interesting to understand the process of regeneration in metazoans.»

In the animal studies, mice containing the gene expressing human resistin and infected with a parasitic worm similar to the human hookworm experienced excessive inflammation, leading to increased weight loss and other symptoms.

She found a gene for what's known as the major histocompatibility complex (MHC)-- cell surface molecules that help the immune system recognize foreigners — that was remarkably similar to one in humans that allows infected people to keep the virus in check for decades.

«Fish eyes to help understand human inherited blindness: Discovery of a gene in zebrafish that triggers congenital blindness could lead to a suitable cure for similar disease in humans..»

Whereas liver and blood gene activity patterns showed the expected differences among the three groupswith human transcription looking similar to that of the chimp, and different from that of the more evolutionarily distant macaquegene activity in the brain revealed stark differences between humans and chimps.

To find out whether Rh proteins perform a similar function, the team knocked out ammonium transporter genes in yeast and replaced them with human Rh protein genes.

They also found a statistically significant, but weaker, correlation between people's genes for BMI and actual BMI in partners: People had actively chosen partners with similar genes to themselves, the team reports today in Nature Human Behaviour.

Its genome has been fully sequenced, its genes are easily manipulated, and many genes found in the fruit fly control similar processes in humans.

Since Chinese researchers announced the first gene editing of a human embryo 2 years ago, many expected that similar work in the United States was inevitable.

Humans have an ortholog of the murine Nrk gene, and considering that the gene expression pattern in breast tumor in Nrk mutant mice was similar to that in human luminal B breast cancer, the findings of this study may lead to further understanding of the mechanisms of human breast cancer suppression and to advances in its diagnosis and therapy.

After removal of similar viral genomes, bootscan plots of the whole genome and individual genes from a subset representing human / simian adenoviruses in species A — G and all non-primate vertebrate adenoviruses were generated.

In addition, mouse brown fat in the collar bone is morphologically similar to human brown fat in the same location, produces compounds involved in the production of heat and expresses genes similar to those expressed by human brown fat.&raquIn addition, mouse brown fat in the collar bone is morphologically similar to human brown fat in the same location, produces compounds involved in the production of heat and expresses genes similar to those expressed by human brown fat.&raquin the collar bone is morphologically similar to human brown fat in the same location, produces compounds involved in the production of heat and expresses genes similar to those expressed by human brown fat.&raquin the same location, produces compounds involved in the production of heat and expresses genes similar to those expressed by human brown fat.&raquin the production of heat and expresses genes similar to those expressed by human brown fat.»