Sentences with phrase «simple model systems»

«These simple model systems can be useful for identifying new drug combinations that act in the context of the whole body.

The researchers are now working with other collaborators to benchmark their experimental results against numerical simulations of the plating process in simple model systems.

Though the biocrusts that the team focused on in this paper comprise a fairly simple model system, they say they plan to apply exometabolomics to more complex soil systems and more microbes.

There is still a lot that is unknown about how pathogens function, but Daniel G. Streicker's interdisciplinary work on bat rabies provides a simple model system for answering key questions on viral emergence and transmission.

Research on the CREB gene emphasizes the reductionist approach, in which elements of the complex phenomenon of memory formation are reduced to mutations in a single gene and studied in a simple model system, the fruit fly Drosophila

Not exact matches

Universal, recurring consumer demand, sophisticated operating system, little organized competition, platform developed by a global leader - it all adds up to a refreshingly simple, yet powerful, model.

Several potential models have been floated, from the simple adjustment of existing insurance rules to a vaccine - like system.

Ford's new ultra-sensitive MyFord Touch system, available this summer in 2011 Lincoln MKX and 2011 Ford Edge models, is designed to respond to 10,000 different simple commands, spoken in a user's natural voice.

The published model was only meant to be broadly representative of the performance one could expect from such a simple system.

These computer simulations of an abstract model (closely related to the features which characterize self - organizing chemical and biological systems) clearly show that the origin of intrinsic capacity for self - definition can be understood in detail, at least in relatively simple cases.

All installed DACS models incorporate Ishida's unique Anti-Floor Vibration (AFV) system, Ishida - made high - sensitivity loadcells and high - speed Digital Signal Processing (DSP) for high weighing accuracy and consistency at high speeds, as well as key pad display for simple operation.

However, modern models offer a simple operation system with just a push of button and some has push - and - hold communication procedure.

In «From funding agencies to scientific agency: Collective allocation of science funding as an alternative to peer review,» the researchers proposed a funding model that they claim would be simpler, cheaper, and fairer than the traditional funding system, and more amenable to high - risk research and chance discovery.

Although the two systems differ greatly in their relaxation time, they are described by the same set of laws, which can be understood from a relatively simple hydrodynamic model.

Three approaches were used to evaluate the outstanding «carbon budget» (the total amount of CO2 emissions compatible with a given global average warming) for 1.5 °C: re-assessing the evidence provided by complex Earth System Models, new experiments with an intermediate - complexity model, and evaluating the implications of current ranges of uncertainty in climate system properties using a simple System Models, new experiments with an intermediate - complexity model, and evaluating the implications of current ranges of uncertainty in climate system properties using a simple system properties using a simple model.

«The way that computer systems learn these complex models these days is that you postulate a simpler model and then use it to approximate what you would get if you were able to deal with all the crazy nuances and complexities,» Campbell says.

Using the freshwater polyp Hydra as a model organism, the Kiel - based researchers and their international colleagues investigated how the simple nervous system of these animals interacts with the microbiome.

Over the next decade a few scientists devised simple mathematical models of the climate, and turned up feedbacks that could make the system surprisingly variable.

Di Ventra's team took advantage of the development this year of memristors — electrical resistors that retain a memory of earlier voltages or currents applied and vary their resistance accordingly — to design a simple circuit that models the amoeba's gel - sol system.

Here, we present experiments using a reconstituted fusion system that suggest a simple model in which the complexin accessory helix forms an alternative four - helix bundle with the target - SNARE near the membrane, preventing the vesicle - SNARE from completing its zippering.

Unlike the Solar System where most of the gravitational pull comes from the Sun and is simple to model, it is much harder to describe the gravitational field near the centre of the Galaxy, where millions of stars, vast clouds of dust, and even dark matter swirl about.

Insects are an important model for the study of emotion; although mice are closer to humans on the evolutionary family tree, the fruit fly has a much simpler neurological system that is easier to study.

Regardless of its origin, analyses of the new ring system — which is much smaller and simpler than those circling Jupiter, Saturn, Uranus, and Neptune — may help scientists develop better computer models of how rings behave and evolve, Burns says.

In a similar way, a duo of theoretical physicists has come up with a way to transform all the disparate members of a vast family of complex systems known as spin models into different shades of a single simple model, which now serves as the one to rule them all.

The simple system that we describe in this paper provides a model that can be further manipulated experimentally for studying those early stages in the evolution of photosynthesis.»

According to co-author Peter Ladurner, an assistant professor at the University of Innsbruck, the worm has many properties that make it a good model system: «M. lignano is small, has simple tissues and organs, is transparent, and has sexual reproduction.»

«Simple models are extremely useful, because analyses and understanding the causes and effects involved is much easier when systems contain few variables,» De Decker added.

The researchers applied a model known as a totally asymmetric simple exclusion process, commonly used to study interacting particles in physical, chemical and biological systems.

The simple body design of stingrays, specifically, a flattened body shape and side fins that start at the head and end at the base of their tail, makes them ideal to model bio-electromechanical systems on.

Given that the degree of under - estimation of TCR using the Otto method seems inversely correlated with the NH / SH warming ratio, at least in the models used in Shindell (2014), it would seem that the rather large NH / SH warming ratio observed in the «real» earth system indicates a tiny to non-existent underestimation of TCR when using those simple methods (e.g. Otto et al) in the real world.

This research, performed under controlled conditions in a simple model, will support a systems - level understanding of universal relationships between genotype, environment, and phenotype.

Moreover, similar answers were found in different climate models, suggesting that this is a very simple way of ascertaining some of the mechanisms that can explain climate system response to climate change.

The usual procedure goes like this: you have a complex physical system and attempt to explain its behaviour through as simple a model as...

No matter how powerful the computer used or how impressive the model output, any model of a natural system is only as good as the authors» understanding of the interaction between the physical laws that define their subject and the potential of simple small - scale interactions to produce large - scale complexity, more readily summarised as:

Despite its power, RNAi is amazingly simple to perform in the roundworm C. elegans, an important model system for eukaryotic gene function.

George was interested in using a vertebrate model that was physiologically simpler than the mouse, so that he could study the development and function of the nervous system.

Clocking in at 302 neurons, it is one of the simplest model organisms to possess a nervous system.

LOS ALAMOS, N.M., Jan. 31, 2018 — Using a simple analytical framework for random events within a predictable system, computational biologists have found a new way to accurately model certain forms of gene expression, including the body's 24 - hour internal clock.

Drosophila imaginal discs, simple epithelial invaginations that grow one thousand fold in mass and cell number, are probably one of the best model systems to analyze at the genetic and molecular level the control of size in a growing epithelium.

Another approach uses the response of climate models, most often simple climate models or Earth System Models of Intermediate Complexity (EMICs, Table 8.3) to explore the range of forcings and climate parameters that yield results consistent with observations (Andronova and Schlesinger, 2001; Forest et al., 2002; Harvey and Kaufmann, 2002; Knutti et al., 2002, 2003; Forest et al., models, most often simple climate models or Earth System Models of Intermediate Complexity (EMICs, Table 8.3) to explore the range of forcings and climate parameters that yield results consistent with observations (Andronova and Schlesinger, 2001; Forest et al., 2002; Harvey and Kaufmann, 2002; Knutti et al., 2002, 2003; Forest et al., models or Earth System Models of Intermediate Complexity (EMICs, Table 8.3) to explore the range of forcings and climate parameters that yield results consistent with observations (Andronova and Schlesinger, 2001; Forest et al., 2002; Harvey and Kaufmann, 2002; Knutti et al., 2002, 2003; Forest et al., Models of Intermediate Complexity (EMICs, Table 8.3) to explore the range of forcings and climate parameters that yield results consistent with observations (Andronova and Schlesinger, 2001; Forest et al., 2002; Harvey and Kaufmann, 2002; Knutti et al., 2002, 2003; Forest et al., 2006).

linking probabilistic simple climate models, complex Earth system models, and econometric analyses of historical weathering and climate impacts to project future risks associated with climate change and improve estimates of the social cost of carbon.

To address this problem, the team, comprising Hokkaido University Professor Seiya Kasai, Associate Professor Akihisa Ichiki of Nagoya University, and Senior Researcher Yukihiro Tadokoro of Toyota Central R&D Labs., Inc., established a simple model that excluded friction force, a parameter that they consider negligible in nano - and molecular - scale systems.

By developing a simple chemically defined culture system permitting efficient differentiation of numerous human iPS cell lines toward cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin whose phenotypes are a consequence of complex protein dysregulation within adult cells.

When given a system with infinite variables, a simple model that uses 3 - 4 HIGHLY RELEVANT variables is no less accurate than a complicated model that uses 20 - 30 potentially relevant variables.

Unlike the Naruto: Ultimate Ninja Storm series which is more and more a mess of technical, balance and gameplay issues these days, Brave Soldiers delivers what is a nice, franchise - based fighting game, at first, i was expecting a simple fighting game with some button mashing, however, the game proved me wrong and i fell in love, the combo system, while easy, is a lot more deep than the one in the Naruto games, with all of the characters having two special attacks, two «burst attacks», a knock - away and a launcher respectively, a throw and an ultimate attack (called a «Big Bang Attack»), every character also has an universal dodge - action that sends them behind their enemies while spending one cosmo bar, making bar management that much precious and shielding you from a half - a-hour combo, unlike in the NUNS series, the fighting and the characters are nicely balanced, with every character being fun to play and viable at the same time, the game runs smoothly without frame - rate issues and the cell - shaded graphics, character models, arenas and effects alike are nice to the eye, battles are divided into rounds, with all the tiny nice stuff like character introductions and outros being intact (fun fact: the characters will even comment on their score after the battle), the game also features an awakening system, called the «Seventh Sense» awakening, unlike the NUNS awakening system which became severely unbalanced in the later game, every character simply gains a damage / defense boost, with the conditions being the same for all characters, eliminating situations when one character can use awakening at almost any point in the battle, or one awakening being drastically stronger than the other, the game has a story mode with three story arcs used to unlock characters, a collection mode, tournament modes, a survival mode, a series of special versus modes and online battle modes.

«For example, making up a dance routine for something as simple as the Hokey Cokey to impress our friends, figuring out how to streamline a supply chain business process, developing a computer simulation to model how a new antibiotic will impact on the immune system, or just doing long multiplication, are all examples of using algorithms to solve problems.

Abstraction refers to stripping away unnecessary details to develop a generic solution, or representing a complicated system with a simple model or visualization.

Today's factory - model education system, which was built to standardize the way we teach, falls short in educating successfully each child for the simple reason that just because two children are the same age, it does not mean they learn at the same pace or should follow the same pathway.

The Enclave offers two all - wheel - drive systems, a simpler system that is optional ($ 2,000) for the Essence trim and a more sophisticated system for the Premium and Avenir models ($ 2,300) that adds a twin - clutch rear differential to shift torque between the left and right rear wheels in addition to between the front and rear — up to 40 percent to the rear in most situations — for both better traction and handling.

The Enclave offers two tiers of all - wheel drive: a simpler system ($ 2,000) that's optional on the Essence trim, and a more sophisticated system ($ 2,300) for Premium and Avenir models.