Sentences with phrase «single cell genomic»

This session featuring Drs. Cai, Bader, Koszul, and Satija, will highlight the design of new biological systems and downstream analyses, single cell genomic profiling of complex biological systems, and the evolution and diversity of biological networks.

His lab develops novel single cell genomic and epigenomic methods to characterize the immune system and develop new targets for immunotherapy.

Using the oral microbial community as a model system, we are applying functional genomic approaches including Stable Isotope Probing (SIP), metatrascriptomics and directed single cell genomic approaches to enable us to overcome this limitation.

The researchers used single cell genomic sequencing, a very useful and still comparatively new capability.

«It's the same process as for single cell genomics, but for aggregates of symbiotic bacteria and archaea,» said DOE JGI Microscale Applications Group head Rex Malmstrom of the technique called BONCAT - FACS (BONCAT — Fluorescence - Activated Cell Sorting).

Topics for the scientific sessions are: Single cell genomics and gene expression Genetic interactions RNAi and somatic cell genetics Protein - DNA interactions Cancer The meeting also highlights existing opportunities for academic and industrial researchers to access automated cell - based and biochemical technologies based at the Karolinska High Throughput Center; home to one of the most sophisticated, state - of - the - art, ultra-high performance liquid handling and analysis platforms in Europe.

«Single cell genomics can be applied to understand the heterogeneity of tumors, to explain how genetically identical cells may show distinct behavior, and to explore the vast, uncharacterized microbial landscape.

Currently, we are exploring several environmental samples retrieved from allover the world - ranging from hydrothermal vents in Japan to hot springs in Yellowstone National Park and New Zealand — for the presence of novel archaeal (and bacterial) lineages using cultivation - independent approaches, such as metagenomics and single cell genomics.

Single cell genomics is an emerging technology enabling the exploration of genomes of individual microbial cells without the need for prior cultivation.

Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates — Jürgen F H Strassert, ISME

Scientific programs include: human genomic sequencing and analysis, synthetic genomics and exploration of new vaccines using this technology, and environmental and single cell genomics to explore the vast unseen world of microbes living in the human body, the ocean, soil and air.

My lab is dedicated to explore the vast uncharacterized microbial diversity using cutting - edge culture independent technologies, such as single cell genomics and metagenomics.

The topics will be single cell genomics and transcriptomics of unknown microbial species.

With single cell genomics, we have a tool that gives us this information from each individual, with all their diversity included.

Recognizing the remarkable opportunities to apply single cell technologies to major questions in biology and medicine, JAX recently launched a joint center for single cell genomics together with the University of Connecticut, including UConn Health.

Our experience in single cell genomics is unique in Spain and suits research on virtual every species, tissue or disease context.

Paul Robson, who serves as JAX Genomic Medicine's director of single cell genomics, believes the work of the new center will be critical to advancing the goals of precision medicine: «If you want better insight into how biology works, you need to look at its fundamental unit,» he says.

Although the field of single cell genomics is still fairly new, it is already becoming clear that cells once thought to be genetically similar, if not identical, are in fact quite different.

Connection to SciLifeLab: Director at the Single cell genomics facility.

Single cell genomics: thinking small by Iain Macaulay We all emerged from a single cell and it only takes a mutation in a single cell to cause disease.

Together with Anna - Maria Divne, I am setting up and establish methods for single cell genomics, from single cell sorting, to whole genome amplification, target screening and sequencing library preparation.Why can you find me on this homepage?

Single cell genomics means that one can study the genetic material of single cells.

During the fall of 2011 he first became involved in SciLifeLab when helping to start up the facility for single cell genomics, which he is also director of.

I started working on my current project revolving around single cell genomics!

Not exact matches

Zhang's group is moving beyond bulk sequencing of tumor samples and is now conducting genomics on single cells.

«We feel it's critical that the scientific community consider the potential hazards of all off - target mutations caused by CRISPR, including single nucleotide mutations and mutations in non-coding regions of the genome,» says co-author Stephen Tsang, MD, PhD, the Laszlo T. Bito Associate Professor of Ophthalmology and associate professor of pathology and cell biology at Columbia University Medical Center, and in Columbia's Institute of Genomic Medicine and the Institute of Human Nutrition.

A study analyzing brain tumor genomics on a single - cell level has found evidence that cancer stem cells fuel the growth of oligodendrogliomas, a slow - growing but incurable form of brain cancer.

SingulOmics and Novogene now work together to offer a complete single - cell genomics workflow as a service.

Like SingulOmics and Novogene, BGI offers a range of single - cell genomics services.

As costs come down and methods become more standardized, experts in the field expect single - cell sequencing to become the new model for both transcriptomic and genomic studies.

The TruePrime Single - Cell Whole Genome Amplification (WGA) kit uses a revolutionary multiple displacement amplification method based on the combination of the recently discovered DNA primase Thermus thermophilus (Tth) PrimPol and the extremely processive, high - fidelity Phi29 DNA polymerase (Phi29 DNAP) to amplify uniformly total genomic DNA of either a single cell or a few Single - Cell Whole Genome Amplification (WGA) kit uses a revolutionary multiple displacement amplification method based on the combination of the recently discovered DNA primase Thermus thermophilus (Tth) PrimPol and the extremely processive, high - fidelity Phi29 DNA polymerase (Phi29 DNAP) to amplify uniformly total genomic DNA of either a single cell or a few ceCell Whole Genome Amplification (WGA) kit uses a revolutionary multiple displacement amplification method based on the combination of the recently discovered DNA primase Thermus thermophilus (Tth) PrimPol and the extremely processive, high - fidelity Phi29 DNA polymerase (Phi29 DNAP) to amplify uniformly total genomic DNA of either a single cell or a few single cell or a few cecell or a few cells.

In a recent proof - of - concept experiment, Abate and his colleagues performed single - cell genomic sequencing on a sample of seawater.

This mechanism therefore ensures that reprogramming is completed within one cell cycle and protects genomic integrity at the volatile single - cell embryo stage.

They elaborate on several focus areas described by the White House earlier: preventive vaccines, early detection, single cancer cell genomics, immunotherapy, pediatric cancer, and data sharing.

Recent advances in single - cell genomics technology has made it possible to separate individual cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each cell its own identity.

Using this method, features of genomic organization including compartments, topologically associating domains (TADs) and chromatin loops were detected in single cells when averaged over the genome.

The experimental plan includes a fine - grained analysis of the different cell populations within these precious tissues using cutting - edge single - cell genomics methods.

The team, which also includes Raul Rabadan, PhD, professor of systems biology and biomedical informatics at CUMC, will use single - cell genomics to create a unique, genetic ID tag for each cell in the spinal cord.

For example, the BRAIN Initiative supports a series of projects that are characterizing mammalian brain cell types using single - cell genomic analysis.

«Over the last several years, single - cell genomics has become a popular tool to complement metagenomics,» said study senior author Tanja Woyke, head of the DOE JGI Microbial Program.

His thesis was entitled «Elucidating cancer evolution using single - cell sequencing and comparative genomics.»

Published in Nature, the single - cell genomics study was led by the European Bioinformatics Institute (EMBL - EBI) and the University of Cambridge.

Recent advances in single - cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.

To do so, she will use novel cultivations - independent techniques such as metagenomics and single - cell genomics, but also more

These types of investigations have been enabled by key technologies, including single - cell assays, high - throughput genomic sequencing, and improved bioinformatic algorithms.

Courtney did her PhD at Dalhousie University (Halifax, Canada) and recently joined Ettema - lab to investigate the diverse protist biology using single - cell genomics and transcriptomics.

The Vijayanand lab has developed a number of genomics (transcriptomic, single - cell and epigenomic) and immunological assays to enable research with small numbers of cells and small - volume clinical samples.

The Swedish Biodiversity Program aims to target biodiversity of bacteria, viruses, archaea and eukaryotes and combinations thereof to promote large research projects aiming to uncover and understand genomic variability in nature by use of massively parallel sequencing and microbial single cell analysis.

Single - cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types.

Alexander J, Kendall J, McIndoo J, Rodgers L, Aboukhalil R, Levy D, Stepansky A, Sun G, Chobardjiev L, Riggs M, Cox H, Hakker I, Nowak DG, Laze J, Llukani E, Srivastava A, Gruschow S, Yadav SS, Robinson B, Atwal G, Trotman L, Lepor H, Hicks J, Wigler M, Krasnitz A. Utility of single - cell genomics in diagnostic evaluation of prostate cancer.