«We described a novel method to directly examine the transcription pattern of genotypic variants
at single cell resolution,» explained Dr. Jan Vijg, Department of Genetics, Albert Einstein College of Medicine, lead author of the paper.
Similarly, spatially defined molecular measurements of gene expression can now be made on thousands of genes
in single cell resolution.
It would be clearly synergistic for a huge community of researchers and clinical scientists if current and future efforts to study model systems
at single cell resolution (mouse, fly, worm, organoids, and many others) would join forces and combine methods and data handling / interpretation within the HCA and vice versa.
Rather than analyzing groups of cells, they performed a comprehensive analysis of the genes that are expressed in the different cells at
a single cell resolution.
The Lac - Operon has been studied for more than 50 years, and still, we discovered new important properties when looking at it with
single cell resolution,» says van Nimwegen.
Wound healing assays have
single cell resolution, however the results are confounded by frequent interactions between moving cells.
The Human Cell Atlas aims to provide a reference map of the human body at
single cell resolution.
A technical focus is CyTOF mass cytometry, which uses heavy metal - conjugated antibodies in tandem with time of flight mass spectrometry to measure protein abundances at
a single cell resolution.
Ettema Lab is pleased to announce the new paper in Current Biology by Henning Onsbring Gustafson on cellular regeneration in the ciliate Stentor at
single cell resolution.