A new study used
single cell sequencing technology to provide previously...
Not exact matches
Single -
cell DNA and RNA
sequencing technologies are entering the marketplace.
The kit also preserves the
single - nucleotide variants (SNVs) and SNV frequencies across different
sequencing technologies and allows the amplification of
cell - free DNA to levels that permit
sequencing.
This family tree captures just a sampling of
single -
cell and
single - nucleus RNA
sequencing technologies that have burst onto the scene over the last eight years.
This led to development of newer
technology, called
single cell sequencing (SCS), that has had a major impact in many areas of biology, including cancer research, neurobiology, microbiology, and immunology, and has greatly improved understanding of certain tumor characteristics in cancer.
Existing
technology, known as next - generation
sequencing (NGS), measures genomes derived from millions of
cells versus the newer method for
single -
cell sequencing, called Monovar.
Here they photographed organisms from deep - water samples and used
technology to
sequence the genomes of these
single -
celled organisms.
UCLA scientists, in collaboration with teams in China, have used the powerful
technology of
single -
cell RNA
sequencing to track the genetic development of a human and a mouse embryo at an unprecedented level of accuracy.
This includes the development of advanced laboratory tools such as CRISPR genome - editing and
single -
cell sequencing technologies.
The Korbel group combines experimental and computational approaches, including
single -
cell sequencing technology, to unravel determinants and consequences of germline and somatic genetic variation.
These types of investigations have been enabled by key
technologies, including
single -
cell assays, high - throughput genomic
sequencing, and improved bioinformatic algorithms.
Scientific programs include: human genomic
sequencing and analysis, synthetic genomics and exploration of new vaccines using this
technology, and environmental and
single cell genomics to explore the vast unseen world of microbes living in the human body, the ocean, soil and air.
Research Focus: I dedicate my time and effort to develop high - throughput
sequencing technologies such as
single cell transcriptomic, ChIP - Seq, ChIA - PET, and many more... The scientific rational is to understand better and with a different angle, the mechanisms of epigenetic regulation of gene expression in (rare) immune
cells, pathologically relevant in many diseases such as asthma, SLE, tuberculosis...
The recent developments in high throughput
single -
cell RNA
sequencing technology (scRNA - seq) have enabled the generation of vast amounts of transcriptomic data at cellular resolution.