The Single Cell Genomics Team at CNAG is dedicated to advance genome research of single cells and targets to enable the researchers to use
single cell technology in scalable and affordable manner.
Beside Microbiology and Evolution, research areas like Complex tissues, Neurobiology, Immunology and Cancer are among the top fields that
single cell technology is being used.
Nowadays many researchers are interested to take advantage of
single cell technology to answer questions like:
In this project, the researchers used
single cell technology to explore gene expression patterns in healthy and diseased hearts.
Recognizing the remarkable opportunities to apply
single cell technologies to major questions in biology and medicine, JAX recently launched a joint center for single cell genomics together with the University of Connecticut, including UConn Health.
Not exact matches
While a
single cell or landline might work for some small businesses, Integrated
Technology's complex needs demand a more sophisticated solution.
Everything from
single cell organisms, to our DNA, to manufacturing, to emergent
technologies.
In giant vats, muscle and fat
cells will be cultured then made into so - called «clean meat», without, if the
technology progresses, a
single animal having to die.
What if we have
technology that can detect a
single cancer
cell in the body?
Bracknell, UK, 3 November 2014 — Diversified
technology company 3M has announced availability of a unique
single - use platform that removes host
cell DNA (HcDNA) and proteins (HCP) in various applications within the bioprocessing industry.
Single -
cell DNA and RNA sequencing
technologies are entering the marketplace.
The kit also preserves the
single - nucleotide variants (SNVs) and SNV frequencies across different sequencing
technologies and allows the amplification of
cell - free DNA to levels that permit sequencing.
We're moving ahead with CNG, fuel
cells, plug - in hybrids and battery electrics because there is no
single technology that holds the key to the world's energy future,» said Robert Bienenfeld, senior manager of environment and energy strategy for American Honda.
«What we want this
technology to achieve is confidence to switch to
single embryo transfers instead of the practice of transferring multiple embryos without [an accompanying] reduction in pregnancy rate,» study co-authors Gayle Jones and David Cram, senior research scientists in immunology and stem
cells at Monash University in Australia, wrote in an e-mail.
In June 2012, physicist Jeff Gore of the Massachusetts Institute of
Technology in Cambridge and colleagues reported that they had induced critical slowing down in laboratory populations of these
single -
celled fungi.
Using the new methods of micromachining, which borrow
technology for making computer chips to carve out and build up microscopic structures on silicon wafers, Peter Gammel and his colleagues at Bell Labs / Lucent Technologies reduced three of the critical devices of a
cell phone to Lilliputian size that will allow all the components of a phone to be constructed on a
single chip.
This family tree captures just a sampling of
single -
cell and
single - nucleus RNA sequencing
technologies that have burst onto the scene over the last eight years.
These
technologies offer a powerful set of tools for biological analysis at the molecular and
single -
cell level in the life sciences, pharmaceutical, and clinical laboratory industries.
A team of multidisciplinary researchers with expertise spanning biotechnology, information
technology, and medicine have used a combination of several «omics
technologies to map proteins down to the
single cell level, showing both proteins restricted to certain tissues — such as the brain, heart, or liver — and those present in all tissues.
The team makes it clear that it thinks its approach is superior to one reported last month in Nature by scientists at Advanced
Cell Technology (ACT) in California — deriving an ES cell line from a single cell taken from a morula (ScienceNOW 23 Augu
Cell Technology (ACT) in California — deriving an ES
cell line from a single cell taken from a morula (ScienceNOW 23 Augu
cell line from a
single cell taken from a morula (ScienceNOW 23 Augu
cell taken from a morula (ScienceNOW 23 August).
However, although the researchers have demonstrated DNA - PAINT's potential by visualizing
single biomolecules, such as proteins, in fixed
cells at a fixed close distance, the
technology could not yet be applied to investigate molecules deep inside of
cells.
In 2008 a group of medical researchers led by Robert Lanza at Advanced
Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic c
Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem
cell line from a single embryonic c
cell line from a
single embryonic
cellcell.
Recent advances in
single -
cell genomics
technology has made it possible to separate individual
cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each
cell its own identity.
Recently,
technology had advanced to the point that scientists could analyze
single cells in those samples.
He has worked in the biotech industry as a research scientist for over 11 years with a focus on emerging
technologies including gene targeting in mice, molecular analysis of transgenes using GFP variants at the
single cell level, and developing flow cytometry reagent kits to speed up assay development time for researchers.
This led to development of newer
technology, called
single cell sequencing (SCS), that has had a major impact in many areas of biology, including cancer research, neurobiology, microbiology, and immunology, and has greatly improved understanding of certain tumor characteristics in cancer.
Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a
single cancer
cell versus current
technology that analyzes millions of
cells which they believe could have important applications for cancer diagnosis and treatment.
Using novel
technologies developed at HMS, the team looked at how a
single sensory experience affects gene expression in the brain by analyzing more than 114,000 individual
cells in the mouse visual cortex before and after exposure to light.
The second high - impact / high - risk grant received will be used to explore a new
technology to rapidly detect cancerous
cells inside a
single blood sample.
Existing
technology, known as next - generation sequencing (NGS), measures genomes derived from millions of
cells versus the newer method for
single -
cell sequencing, called Monovar.
The
technology, whose inventors won the Nobel Prize in 2014, can illuminate what's happening in a
cell, right down to a
single molecule.
Here they photographed organisms from deep - water samples and used
technology to sequence the genomes of these
single -
celled organisms.
As this quick survey of the fuel -
cell market shows, the interest and excitement around Bloom's
technology is understandable, but more thanks to the underlying
technology's potential than to a
single, PR - savvy company.
UCLA scientists, in collaboration with teams in China, have used the powerful
technology of
single -
cell RNA sequencing to track the genetic development of a human and a mouse embryo at an unprecedented level of accuracy.
Future optimization of recombination efficiencies achievable by SCRIBE could lead to more efficient
single -
cell digital memories and enhanced genome engineering
technologies.
The
technology the team used is called
single -
cell phosphoproteomics.
The main advantage of using
single -
cell RNA - Seq
technology is it provides a blueprint of gene activity in each and every
cell type.
Systems Biology and Genomics, including systems neurobiology, quantitative
cell biology, cellular dynamics, algorithms, methods and
technology development, data integration and visualization, imaging, synthetic biology, deep learning applied to biology and human health, and
single cell biology.
This includes the development of advanced laboratory tools such as CRISPR genome - editing and
single -
cell sequencing
technologies.
Topics for the scientific sessions are:
Single cell genomics and gene expression Genetic interactions RNAi and somatic
cell genetics Protein - DNA interactions Cancer The meeting also highlights existing opportunities for academic and industrial researchers to access automated
cell - based and biochemical
technologies based at the Karolinska High Throughput Center; home to one of the most sophisticated, state - of - the - art, ultra-high performance liquid handling and analysis platforms in Europe.
William Ratcliff, a biologist at the Georgia Institute of
Technology in Atlanta, and his collaborators have discovered a surprisingly simple route to multicellularity: a
single mutation in yeast that adheres the mother
cell to its daughter to create a snowflake - like shape.
Studying cancer with
single -
cell technology will allow us to unlock the interactions between different types of
cells in tumors — and monitor how these interactions change over time, affecting patients» outcomes.
diSPIM
technology enables rapid 3D imaging of samples ranging from
single cells to small organisms over the course of hours to days.
Single -
cell technologies will be applied to experimental model systems such as organoids, miniature organs grown in the petri dish from one or more
cells.
The Korbel group combines experimental and computational approaches, including
single -
cell sequencing
technology, to unravel determinants and consequences of germline and somatic genetic variation.
For the other adult patients that might still benefit from a cord blood donor, either two cord blood units are combined for a
single transplant, or more recently, there are some exciting new graft engineering
technologies that are emerging to expand stem or progenitor
cells in the laboratory before infusion or modify the
cells in some way to make them more potent at the time of transplant.
Single cell genomics is an emerging
technology enabling the exploration of genomes of individual microbial
cells without the need for prior cultivation.
These types of investigations have been enabled by key
technologies, including
single -
cell assays, high - throughput genomic sequencing, and improved bioinformatic algorithms.
This research makes use of
single - molecular fluorescence imaging
technology to visualize and analyze the behavior of exogenous DNA that were introduced into the
cell from outside.
Our study demonstrates the power of combining the BD AbSeq
technology with RNA - seq to gain a more comprehensive understanding of
cell lineage and function at the
single -
cell level.