The tumors formed in mice co-treated with chidamide and decitabine were significantly smaller than those that formed in untreated animals or those treated with the
single agents, starting from 15 days of treatment (
Figure 4C, left panel), as visualized by 18F - fluorodeoxyglucose small - animal positron
emission tomography — computed tomography at 21 days of treatment (
Figure 4C, right panel).