Martienssen, Couture, and Yannick Jacob, Ph.D., a postdoctoral fellow at CSHL and lead author on the paper, found that the key was
a single epigenetic modification.
The TMWG kit incorporates Cambridge Epigenetix's TrueMethyl oxidative bisulfite (oxBS) technology, which allows researchers to accurately quantify different DNA
modifications at
single - base resolution, as well as proprietary library preparation methods designed to overcome the limitations of traditional bisulfite library construction, and to improve the yield and quality of
epigenetic data.