But an alternative explanation is that inheriting recessive copies of
a single gene from both parents often, but not always, causes the disorder.
Not exact matches
Previous studies in nearly 3000 HIV - infected people had failed to uncover a
single person who had inherited copies of the mutated
gene that produces the CCR5 protein
from both
parents.
Individual screening tests can already identify silent carriers of many
single faulty recessive
genes — the kind that, when inherited in double (one copy
from each
parent), can lead to conditions such as cystic fibrosis and Tay - Sachs disease.
Phenotypes that result
from changes (i.e., variants) in a
single gene (i.e., monogenic) and that can be transmitted
from parents to offspring in Mendelian patterns, such as autosomal dominant, autosomal recessive, X-linked, are known as Mendelian phenotypes.
This may be true in a first generation cross (F1) because to inherit a genetic disease which is caused by a
single recessive
gene, offspring would need to inherit the
gene from both
parents.
Not nearly as simple as those due to a
single pair of defective recessive
genes that some offspring inherit
from their
parents.