Sentences with phrase «single gene loci»

The pre-publication data that we release via this website is embargoed for publication except for analyses of single chromosomes in single strains or single gene loci across multiple strains.

The Canadian Patent Office would have to reverse the Patent licenses it has granted to companies who have received them for what's called single gene loci.

Not exact matches

By using engineered zinc - finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one - cell rat embryo leads to a high frequency of animals carrying 25 to 100 % disruption at the target locus.

The genomics era has had a profound impact on life science research, leading to significant developments such as the use of expression quantitative trait loci (eQTLs), which link polymorphisms in single genes to quantifiable changes in gene expression associated with specific diseases.

Scientifically, the success was the engineering of a gene cassette containing four genes for the micronutrient improvement that could be inserted into the rice genome as a single genetic locus.

Multiple transcripts arising from alternative initiation or polyadenylation sites, or alternative RNA splicing at a single locus were not considered as multiple genes but as variants of a single transcription unit.

Single loci with major effects in fire ants: the effects of the complementary sex - determining locus and the green beard supergene on gene expression

«It's hard to fit every single locus in the genome into one specific model of gene regulation.

Methods.: Dogs of various breeds, affected or unaffected with primary glaucoma, were genotyped for the Gly661Arg variant of ADAMTS10, as well as 7 other nonsynonymous single nucleotide polymorphisms (SNPs) in other genes in the beagle POAG locus that segregate with disease.

In their work on compulsive blanket and flank sucking in Dobermanns, the authors identified a single locus with genome - wide significance within the gene Cadherin 2 (cdh2), a widely expressed gene involved in pre - and post-synaptic adhesion.