Sentences with phrase «single gene on chromosome»

When the researchers compared the mRNA to a library of DNA sequences taken from the dendrites of neurons by James Eberwine of the University of Pennsylvania Medical Center, they found that it came from a single gene on chromosome X — the human version of which, when mutated, leads to fragile - X syndrome.

Not exact matches

On the other hand, gene variants that confer a benefit to males are more likely to accumulate on the X chromosome than on a nonsex chromosome because they will always be expressed on a male's single X chromosomOn the other hand, gene variants that confer a benefit to males are more likely to accumulate on the X chromosome than on a nonsex chromosome because they will always be expressed on a male's single X chromosomon the X chromosome than on a nonsex chromosome because they will always be expressed on a male's single X chromosomon a nonsex chromosome because they will always be expressed on a male's single X chromosomon a male's single X chromosome.

Reviewing thousands of genome wide associate studies (GWAS) to identify genetic variants in single nucleotide polymorphisms (SNPs), investigators at Dartmouth's Norris Cotton Cancer Center found that some alleles (one of a pair of genes located on a specific chromosome) are more frequently risk - associated with disease than protective.

In Angelman's syndrome a child receives two copies of genes on chromosome 15 from his or her father, and a single inactivated copy of those genes from his or her mother.

Now they have singled out a gene on the chromosome.

But then a gene on a single chromosome mutated in a way that made any individual that inherited it male.

That's unusual; most microbial genomes consist of a single chromosome, sometimes with some extra genes carried on bits of extraneous DNA called plasmids.

For more than two decades we've known that a single gene on the Y chromosome, called Sry, is responsible for male sex determination.

Fragile X, which is caused by a mutation in a single gene on the X chromosome, affects about 1 in 4,000 men and 1 in 6,000 women.

This may be especially useful as it sheds light onto why class I genes remain on a single region on one chromosome during mammalian evolution, while class II genes do not.

Other medical sequencing projects will use DNA sequencing to: discover new genes that are involved in common diseases; identify the genes responsible for dozens of relatively rare, single - gene (autosomal Mendelian) diseases; sequence all of the genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in genes known to contribute to certain common diseases.

Analysis of a linkage peak on chromosome 13 with a dense set of SNPs (single nucleotide polymorphisms) revealed a four - SNP haplotype spanning the gene encoding FLAP (ALOX5AP) that confers an approximately twofold increased risk of myocardial infarction, or heart attack.

Researchers have achieved new insights into how the global control of all genes on a single chromosome can be established and maintained throughout the lifetime of an organism.Their findings about...

In the first paper, utilizing genomic analysis of nearly 8,500 Icelandic and Dutch participants, the deCODE team identified a novel, tightly - linked pair of single - letter variants (SNPs) near the ASIP (agouti signaling protein) gene on chromosome 20 that greatly increase the likelihood of an individual being prone to freckles and sunburn.

Genome - wide analysis of CNVs revealed that a single copy of the mdr1 gene on chromosome 5 and a novel amplification of the plasmepsin 2 and plasmepsin 3 genes on chromosome 14 also associate with raised piperaquine IC ₅₀ s.

The human DAO gene spans ≈ 10 kbp and is located on chromosome 7q35 (27) Various single - nucleotide polymorphisms (SNPs) in the DAO gene have been shown to be associated with inflammatory and neoplastic gastrointestinal diseases, such as food allergy (44), gluten - sensitive enteropathy, Crohn disease, ulcerative colitis, and colon adenoma (45 — 47).

These traits are controlled by a single gene that is ultimately located on a single chromosome pair.