Sentences with phrase «single gene promoter»

Not exact matches

Single - cell mouse embryos were infected in vitro with recombinant lentiviral vectors to generate transgenic mice carrying the green fluorescent protein (GFP) gene driven by a ubiquitously expressing promoter.

In a second series of experiments, Fukaya showed that a single enhancer can activate simultaneously two genes that are located some distance apart on the genome and have separate promoters.

When genes are heavily transcribed, they have a tendency to form single - stranded DNA loops, called R - loops, near their promoter.

First, Dr. Shendure described some interesting experiments under way in his lab to elucidate the function of non-coding regulatory variants — specifically, single nucleotide changes in the core promoter that alter gene transcription.

Single - cell experiments show that gene expression is random and «bursty,» Lin said, a feature that can emerge from slow switching between promoter states with different activities.

The data indicate that the epigenetic response to maternal care involves not only single candidate gene promoters but includes transcriptional and intragenic sequences, as well as those residing distantly from transcription start sites.