In the lab, he and colleagues exploit the natural diversity of plant genomes to identify sets of genes and
single genes responsible for genetic variation.
Kapahi said this research could help explain why scientists are having a difficult time identifying
single genes responsible for the long lives experienced by human centenarians.
A single gene responsible for type 1 disease has been identified.
Oxford University researchers have discovered, for the first time,
a single gene responsible for increasing insulin sensitivity in humans.
This condition has a genetic component, but there is
no single gene responsible for the condition.
Not exact matches
Almost immediately such familial genome sequencing proved its value, uncovering mutations
responsible for diseases caused by defects in a
single gene.
The research team used
single -
gene amplification to study the
gene responsible for HIV's major surface protein, env.
Huntingtin, the
single gene mutation
responsible for the disease, was identified in 1993.
Now researchers have identified a
single gene, called fruitless (fru), as
responsible for the development of male sexual behavior in the fly.
«This experiment confirmed that this
single gene was
responsible for all these changes,» Dubcovsky notes.
A
single injection of a new treatment has reduced the activity of the
gene responsible for Huntington's disease for several months in a trial in mice.
For more than two decades we've known that a
single gene on the Y chromosome, called Sry, is
responsible for male sex determination.
Thus µSCALE empties the contents of a
single capillary onto a collector plate, where the DNA of the isolated cell can be sequenced and the
gene variant
responsible for the protein of interest can be identified.
Other medical sequencing projects will use DNA sequencing to: discover new
genes that are involved in common diseases; identify the
genes responsible for dozens of relatively rare,
single -
gene (autosomal Mendelian) diseases; sequence all of the
genes on the X chromosome from affected individuals to identify those involved in sex - linked diseases; and survey the range of variants in
genes known to contribute to certain common diseases.
Mutations in the
genes SLC24A5 and SLC45A2 are largely
responsible for European pigmentation, showing only
single amino acid differences between Europeans and West Africans.
Scientists used
gene chips containing feline
single nucleotide polymorphisms (SNPs)-- variations from the common feline DNA sequence that can help track down
genes responsible for genetic diseases — to conduct their investigations.
Homozygosity mapping of 5 cases (4 full - sibs, 1 half - sib) and 5 controls (2 parents, 3 full - sibs) via Illumina CanineHD SNP genotyping BeadChips identified a
single chromosome (canine chromosome 36; CFA36) of interest where the
gene containing a
responsible mutation is expected to be located.