Sentences with phrase «single nucleic»

Ronald W. Davis, Ph.D., Stanford University, Stanford, Calif. $ 450,000 (2 years) «Single Molecule Nucleic Acid Detection with Nanopipettes» This group takes a stepwise approach to single nucleic acid molecule detection, using the nanoscale pore in a pulled glass pipette to measure single DNA molecules with attached nanoparticles.

His suspicionswas confirmed: the children had an identical defect — a missing single nucleic acid, called guanine — in the gene coding for leptin.

Using a combination of old - fashioned clinical observation and modern biochemical analysis, he has shown that a person's appetite and their eating behavior can be linked to specific genes — and that even a tiny defect such as the absence of a single nucleic acid in a sequence of DNA can lead to runaway weight gain.

Not exact matches

The Zika virus helicase is a motor enzyme that converts energy from nucleoside triphosphate to unwind and separate double - stranded nucleic acids, so the single - stranded genetic material can then be copied.

These improvements push the boundaries of nucleic - acid detection and fragment sizing, affecting applications such as single - cell nucleic acid analysis, PCR - free preparation of NGS library preparation, bacterial artificial chromosome clone sizing, and exosome analysis.

A new nucleic acid sequencing platform, the Sequel System, provides higher throughput, more scalability, a reduced footprint, and lower sequencing project costs compared to the PacBio RS II System, while maintaining the existing benefits of single molecule, real - time (SMRT) technology.

Optical imaging and spectroscopy, advanced optical imaging techniques in particular super-resolution fluorescence microscopy, optical physics, nanotechnology, single - molecule biophysics and macromolecular biochemistry, single - molecule imaging, gene expression, computational modeling, single - molecule (force) spectroscopy, biomolecular engineering, nucleic acid nanotechnology

He'd like a way to perform single - cell analysis using microarrays, instead of full sequencing, but chip - based bisulfite methods require more nucleic acid — about a microgram — than one cell can provide.

In 1999 the nucleic acid sequence archives contained a total of 3.5 billion nucleotides, slightly more than the length of a single human genome; a decade later they contained more than 283 billion nucleotides, the length of about 95 human genomes.

Functions typically attributed to folded proteins occur inside, such as binding and selectively concentrating single - stranded over double - stranded nucleic acids.

RNA (ribonucleic acid) a single stranded nucleic acid chain similar to DNA, which serves several important biological roles.

Our group seeks to investigate the use of chemically - modified nucleic acid aptamers, single stranded DNA or RNA sequences that specifically bind to a diverse variety of targets, in biosensing and catalysis.

It is a micro-algae single - celled organism that is rich in trace minerals, chlorophyll, essential amino acids, DHA, EPA, carotenoids, antioxidants, nucleic acids and necessary vitamins.