Sentences with phrase «single type of mutation»

Not exact matches

Although they can only change 4 of the 12 possible types of single letter mutation, the ones they target are more common than others.

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

Instead they search specific regions of the genome for a type of mutation known as a single nucleotide polymorphism, or SNP (pronounced «snip»).

The authors acknowledge that «tumor tissue should be considered the preferred sample type when available, however, our encouraging results suggest that a single plasma - derived ctDNA sample may be considered appropriate for assessment of EGFR mutation status when tumor tissue is unavailable or exhausted.»

Navin's team developed Nuc - Sec as a single - cell genome sequencing method and applied it to study how cell mutations occur in both types of breast cancer.

Although mutations come in many varieties, one type, called nonsense mutations, involve the seemingly innocuous change of a single letter in the coded message — a change that causes the gene's message to prematurely read «stop.»

Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure.

They could see the results of recombination as well as other types of mutation, such as single base pair mutations.

Single amino acid mutations in mTOR are found in several types of human cancers, which confer constitutive activation of this autophagy negative regulator [10,11].