Sentences with phrase «sites of copy number»

This is to accommodate small variants that occur at sites of copy number variation as well as in samples that are not pure: for example, due to tumor heterogeneity or sample mosaicism.

Not exact matches

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This murine model system offers a superior source of immortalized cell populations as many of the difficulties associated with the in vitro transfection process are eliminated (e.g., initial requirement for many cells, different sites of gene integration, multiple copy number; Ref.
Methods: Sixty - eight parasites isolates with in vivo clearance data were obtained from two Tracking Resistance to Artemisinin Collaboration study sites in Cambodia, culture - adapted, and genotyped for pfkelch13 and other mutations including pfmdr1 copy number; and the RSA0 - 3h survival rates and response to antimalarial drugs in vitro were measured for 36 of these isolates.
In some species copy number variation (CNV) of target site loci (e.g. the Ace - 1 target site of carbamate insecticides) or detoxification genes has been implicated in the resistance phenotype.
These hotspots may be sites of selective susceptibility to double - strand - break damage due to high transcriptional activity or, through incrementally increasing copy number, may be sites of secondary selective pressure.
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You can set the number of copied words necessary to trigger an alert and choose sites to ignore, which is useful if you've created identical profiles elsewhere.
In the last year though a few competitors have popped up (see yesnomayb, a copy of the business model) and a number of free dating sites also started to eat away at traffic.
To order copies of toronto star articles, please go to: Police and anti-fraud agencies are warning about the increasing numbers of scammers using online dating sites as their main targets.
There are a number of viable cloud solutions for backups that will enable you to maintain an off - site copy of your data.
Thanks to the success of the initial release, Frogger has «spawned» a number of incarnations, including a casino game available on free slot sites and a console version that sold over 20 million copies following its release in 2005.
It released a cracked copy of the game to «the number one torrent - sharing site» itself — a copy of the game with a special Easter egg just for the illegal downloaders.
Many sites state that the cartridge never made it to stores and most of the copies available today were found at a Nintendo warehouse, with production numbers under 2,000.
While I could not locate the electronic copy for this article on the Globe and Mail web site, there are a number of articles on the web telling this same story... with slight variations in the text.
There are a number of viable cloud solutions for backups that will enable you to maintain an off - site copy of your data.
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