Expression of clusterin, a protein implicated in other etiologies of cardiovascular disease, was assessed in canine and murine mucopolysaccharidosis type I aortas via Western blot and in
situ immunohistochemistry.
To determine the structural and chemical composition of the soft tissues Lindgren collected and see if the fossil sea turtle did have a dark colored shell, the researchers subjected the sample to a selection of high - resolution analytical techniques, including field emission gun scanning electron microscopy (FEG - SEM), transmission electron microscopy (TEM), in
situ immunohistochemistry, time - of - flight secondary ion mass spectrometry (ToF - SIMS), and infrared (IR) microspectroscopy.
Not exact matches
They identified ALK - positive mesotheliomas by
immunohistochemistry; confirmed with fluorescence in
situ hybridization; and performed targeted next - generation sequencing of tumor DNA and RNA to get a full picture of the exact genetic rearrangement underpinning the disease.
The Research Histology Core Laboratory includes specialized equipment for
immunohistochemistry, fluorescent in
situ hybridization FISH, laser capture microdissection, and tissue microarray construction.
The department has expertise and infrastructure to support bacterial and viral analysis, and the detailed evaluation of cellular and serological immune responses including flow cytometry and cell sorting, Luminex multiplex platforms, real time PCR, microarrays, comprehensive histological staining,
immunohistochemistry and in -
situ hybridisation.
The lab regularly uses techniques such as dye backfills,
immunohistochemistry, in
situ hybridization, PCR, and confocal microscopy.
Providing laboratory support for through tissue specimen preparation, interpretation, and ancillary techniques, including
immunohistochemistry and in
situ hybridization