After 6 months, the prostate
size in the nettle group was significantly smaller
than that of the
placebo group, and long - term effects of stinging nettle treatment were seen even after discontinuation.
Although venlafaxine and paroxetine had significantly (p < 0.001) larger weighted mean effect
sizes comparing drug to
placebo conditions (ds = 0.42 and 0.47, respectively)
than fluoxetine (d = 0.22) or nefazodone (0.21), these differences disappeared when baseline severity was controlled.