Sentences with phrase «skeletal disease in»

It has also been shown that excessive dietary calcium in large breed puppies is linked to the increase of skeletal disease In light of this, we follow the recommended criteria of: LOW CALORIES, LIMITED CALCIUM and LOW FATS.

It covers feeding to prevent (and treat) skeletal disease in growing pups and feeding for breeding.

Hip Dysplasia commonly occurs in large dog breeds and is the most common skeletal disease in dogs.

Another major factor in the development of skeletal disease in young growing dogs is too much calcium intake.

Mishaela Rubin, MD, Medicine, will receive $ 453,472 over two years from the National Institute on Aging for «Skeletal Disease in Type 2 Diabetes: A Novel Therapeutic Approach for the Elderly.»

Not exact matches

Researchers at the University of Louisville have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies for diseases such as muscular dystrophy.

The so - called Columbian theory of syphilis's spread was based on finding skeletal remains bearing the signature of the disease — thickened leg and arm bones and skull scars — in a suggestive pattern.

In that disease, fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive symptomIn that disease, fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive symptomin muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive symptoms.

Sarcopenia is a disease associated with the aging process, resulting in loss of skeletal muscle mass and muscle strength and / or function in the elderly.

Geneticist Michael Briggs from Newcastle University in Newcastle upon Tyne, U.K., who specializes in skeletal diseases, says it's «highly implausible» that these variants all have detrimental effects and just happened to occur together by chance.

Still the study is «an important first step to show that manipulating AMPK - nNOS signaling at least has the potential to help muscle function in muscular dystrophy,» says Michele whose lab at the University of Michigan Cardiovascular Research Center focuses on inherited forms of skeletal and cardiac diseases.

«The minute you experience it it's impossible to step back and forget it,» says the functional geneticist who runs the skeletal disease program at Regeneron Pharmaceuticals in Tarrytown, New York.

Among priorities in 2011, the government intends to make headway against two diseases that hit China hard: hepatitis B and skeletal fluorosis, which is caused by inhalation of fluorine given off by home coal stoves.

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and caSkeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and caskeletal growth through abnormalities in bone and cartilage.

While she was there, the team discovered a gene that played an important role in Rubinstein - Taybi syndrome, a genetic disease that can cause skeletal abnormalities and mental retardation in patients.

We suggest these observations will have therapeutic implications for skeletal myopathies and systemic diseases such as diabetes and obesity and for the aged population, in which reduced endurance impacts mortality and activities of daily living (57); as well as societal implications in terms of altering athletic performance.

A major aspect of our work centers around transcriptional and epigenetic control of plasticity in cardiomyocytes, smooth muscle, and skeletal muscle in physiology and disease.

In his graduate research, Linsley discovered the gene Stac3 is a component of the excitation - contraction machinery in skeletal muscle and the mechanism by which mutations in that gene cause Native American Myopathy, a rare but devastating congenital diseasIn his graduate research, Linsley discovered the gene Stac3 is a component of the excitation - contraction machinery in skeletal muscle and the mechanism by which mutations in that gene cause Native American Myopathy, a rare but devastating congenital diseasin skeletal muscle and the mechanism by which mutations in that gene cause Native American Myopathy, a rare but devastating congenital diseasin that gene cause Native American Myopathy, a rare but devastating congenital disease.

It is characterized by the wasting of skeletal muscles and caused by progressive degeneration of nerve cells in the spinal cord; the disease leads to increasing muscular weakness, atrophy and premature death due to respiratory problems.

Our laboratory focuses on understanding gene regulation in the cardiovascular system, skeletal muscle, and other metabolic tissues, with the ultimate goal of finding novel therapeutic strategies to prevent and treat cardio - metabolic and - myopathic diseases.

Abstract Type 1 ryanodine receptor (RyR1) is preferentially expressed in skeletal muscle, and mutations in the gene have been associated with malignant hyperthermia, a pharmacogenetic disease, and with several congenital myopathies, including central core disease, multiminicore disease, centronuclear myopathy, congenital fibre type disproportion.

It aims at understanding how mechanisms involved in the control of skeletal muscle Ca2 + + homeostasis and excitation - contraction (EC) coupling operate under normal and disease conditions.

AFM - Téléthon (2015 - 2017): Physiopathology of voltage - activated Ca2 + influx in normal and diseased skeletal muscle (coordinator).

Better understanding of mechanisms underlying skeleton development, adult maintenance, and diseases has led in recent years to new and improved treatments for osteoporosis and a few other conditions, but today most skeletal diseases remain untreatable or incompletely treatable.

The Disease Biophysics Group has three open postdoctoral positions to be filled: 1) One position in skeletal muscle tissue engineering, 2) One position in cardiac muscle tissue engineering, and 3) One position in nanofibers and materials science (no biology background required).

Research Interests: Molecular control of cell fate from stemness to differentiated skeletal and neuronal cell types; SOX transcription factors; skeletal malformation and degeneration diseases; intellectual disability and autism spectrum disorders; mouse genetic models; human pluripotent stem cell differentiation models in vitro

Thus, successful accomplishment of the project will allow the fellow to launch a promising research career in stem cell and molecular genetics relevant to inherited and acquired human skeletal diseases.

New SOXC projects in the laboratory are addressing the roles of SOXCs in other skeletal cell types in development, in adult skeleton maintenance, and in human diseases.

Symposia VIII: Skeletal Muscle Lipid Droplet Biology in Exercise and Disease Experts will present findings on liquid droplet dynamics in fat accumulation and metabolic regulation.

The authors highlight the successful application of both induced pluripotent stem cells and embryonic stem cells for this first example of the in vitro formation of functional and mature skeletal muscle tissue, thereby also establishing the potential for patient - specificity in disease modeling, drug development, and possible muscle repair.

A genetic screening approach to studying bone disease has found nine new genes associated with bone health and suggests a new way to discover genes that may be implicated in human skeletal diseases.

Studies of both elderly subjects and cancer patients have found that the aging and disease related loss of skeletal muscle mass, or sarcopenia, is significantly related to the oxidative shift in the plasma thiol / disulfide redox status.

Infectious disease did indeed cause much suffering among nonindustrialized peoples as soon as they abandoned their traditional diets; the same dearth of nutrients that made them susceptible to these diseases also made them susceptible to tooth decay and a change in skeletal structure in the next generation.

The fatty acids created during fructose metabolism accumulate as fat droplets in your liver and skeletal muscle tissues, causing insulin resistance and non-alcoholic fatty liver disease (NAFLD).

Veterinary acupuncture is prescribed for a variety of conditions ranging from reproductive problems in cows, to musculo skeletal problems such as paralysis or disc pathology in horses and dogs, as well as skin disease and feline asthma in cats, and diarrhoea and incontinence in pets.

Osteoporosis is a disease of the skeletal system in which bones fail to create new tissue and when existing bone tissue breaks down.

A person with insulin resistance will divert a greater proportion of dietary carbohydrate to the liver where much of it is converted to fat (that is, de novo lipogenesis), as opposed to being oxidized for energy in skeletal muscle.30 Although Hellerstein31 has recently reported that de novo lipogenesis contributes only ∼ 20 % of new triglycerides, this greater conversion of dietary carbohydrate into fat, much of it entering the circulation as saturated fat, is a metabolic abnormality that significantly increases risk for diabetes and heart disease.

Maximizing the growth rate in young, growing puppies does not correlate to maximal adult size; however, it does increase the risk of skeletal disease.

Typically, dogs over 40 pounds will be good candidates for a total hip replacement, but your dog must be in good overall health, have a mature skeletal structure, have no medical illnesses, no nerve diseases, and have no other joint or bone problems.

Signs produced by protein deficiency or an improper protein: calorie ratio may include any or all of the following: reduced growth rates in puppies and kittens, anemia, weight loss, skeletal muscle atrophy, dull unkempt hair coat, anorexia, reproductive problems, persistent unresponsive parasitism or low - grade microbial infection, impaired protection via vaccination, rapid weight loss after injury or during disease, and failure to respond properly to treatment of injury or disease.

Appropriate calcium levels are vital in developing a strong skeletal system and aid in preventing orthopaedic diseases like Canine Hip Dysplasia.

It prevents skeletal deformities in growing puppies, helps regulate the immune system to control inflammatory diseases (just like omega fatty acids do), helps to prevent cancer and contributes to skin health.

In young dogs, overfeeding may also accelerate their growth rate, which in some breeds can increase the risk of potentially serious skeletal diseaseIn young dogs, overfeeding may also accelerate their growth rate, which in some breeds can increase the risk of potentially serious skeletal diseasein some breeds can increase the risk of potentially serious skeletal diseases.

The condition may also result in calcified lumps in the skin, susceptibility to skin infections and diabetes, weakening of the heart and skeletal muscles, nervous system disease and other symptoms.

Overnutrition and skeletal disease: an experimental study in growing Great Dane dogs.

Skeletal diseases are often diagnosed in growing dogs, most commonly in large and giant breeds.

Skeletal and growth related diseases were also observed when diets of growing dogs were lacking in calcium [18, 19].

Childhood exposure to household dysfunction and abuse correlates with adverse health outcomes in adulthood.1 The Adverse Childhood Experiences (ACE) Study1 found a relationship between childhood exposure to abuse and household dysfunction and medical disorders in adulthood, including cancer, liver disease, skeletal fractures, chronic lung disease, and ischemic heart disease.