Sentences with phrase «skeletal muscle disorders»

Horses from many different breeds can suffer from the skeletal muscle disorder termed recurrent exertional rhabdomyolysis (RER), also commonly referred to as tying - up, in which an individual exhibits sporadic but recurring bouts of painful cramping and muscle cell damage following mild to moderate exercise.

Not exact matches

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

Pennington Biomedical's research enterprise includes approximately 70 world - class faculty researchers and specialists in neuroscience, stem cell biology, skeletal muscle biology, statistical genetics, diabetes, behavior modification, eating disorders and other areas.

The understanding of this group of disorders has advanced in recent years through the identification of the causative mutations in the gene encoding one of the major proteins of the basic contractile unit of skeletal muscle, i.e., actin.

Their contribution to the formation and maintenance of the contractile apparatus highlight an unconventional role for clathrin flat lattices in skeletal muscle which may be relevant to pathophysiology of several neuromuscular disorders.

These results imply that mutations in the gene encoding RyR1 will not only affect skeletal muscles, but other tissues that express this calcium channel as well, thereby broadening the clinical spectrum of disorders due to RyR1 dysfunctions.

Targeted gene therapy, which would affect smooth muscle cells but not skeletal muscle, holds promise for treatment of these and other disorders.

One theory proposes that once the storage capacity of subcutaneous adipose tissue (SAT) depots is exceeded under conditions of energy excess, either as a result of impaired expandability and / or excessive hypertrophic growth, fat deposition within visceral depots and non-adipose tissues including the liver, skeletal muscle and pancreas can ensue.93 This can subsequently lead to the development of systemic IR and a series of associated cardiometabolic disorders including dyslipidaemia, dysglycaemia, hyperinsulinaemia and hypertension.3 Expression of pro-inflammatory mediators including interleukins 1 (IL - 1), 6 (IL - 6), tumour necrosis factor alpha (TNF - α) and resistin, are also increased which can further potentiate IR and promote atherosclerosis.

They are vilified in the Paleo community because a few studies have shown that lectins can impair growth, linked to autoimmune disorders, damage the lining of the small intestine causing leaky gut, destroy skeletal muscle, and interfere with the function of the pancreas.

Fibromyalgia is a chronic disorder that causes muscle and skeletal pain across the body.

She adds, «To prevent orthopedic issues — such as disorders of the skeletal system and associated muscles, joints and ligaments — we try to slow down their growth.»

The ailments acupuncture for dogs can heal include skin disorders, internal organ disorders which otherwise may require complicated and possible fatal surgery, muscle and skeletal abnormalities, painful joints due to arthritis and loss of bone strength, neurological illness, female dogs reproductive issues as well as male dogs with problems siring litters of pups.

Disruption of signal transmission within the NMJ resulting from presynaptic, synaptic, or post-synaptic defects causes congenital myasthenic syndromes (CMSs), heterogeneous neuromuscular disorders characterized by skeletal muscle weakness and fatigue.

Congenital myasthenic syndromes (CMSs) are heterogeneous neuromuscular disorders characterized by skeletal muscle weakness caused by disruption of signal transmission across the neuromuscular junction (NMJ).

Lack of vitamin A in puppies directly relates to retarded growth rates, weakness in the muscle, vision problems, a poor coat condition, skeletal and nervous disorders such as hydrocephalus and cleft palate.

Orthopedics is the branch of medicine that deals with the prevention or correction of injuries or disorders of the skeletal system and associated muscles, joints, and ligaments.