Sentences with phrase «skeletal muscle fatigue»
I now propose to tackle the new problem of the molecular basis of skeletal muscle fatigue, particularly as it relates to loss of muscle function with aging.
http://www.ellisonfoundation.org/ Not exact matches
Highly intensive and / or long - lasting physical activity can lead to muscle fatigue and the depletion of glycogen stores in skeletal muscle.
To address the fatigue characteristics of isolated skeletal muscles, we dissected the fast extensor digitorum longus (EDL) and slow soleus muscles from anesthetized mice and subjected them to a repeated contraction protocol in which muscles were stimulated for 330 ms every second for 6 minutes at a stimulation frequency of 40 Hz.
Our data demonstrate that loss of IL - 15Rα results in a remodeling of fast skeletal muscles to a more oxidative phenotype that manifests as a greater exercise capacity and resistance to fatigue in mice due, in part, to adaptations in mitochondria — phenotypes that were only observed in IL - 15Rα — KO mice.
Resistance to repeated contraction - induced fatigue is a hallmark characteristic of slow skeletal muscles such as the soleus and is due to a combination of increased mitochondrial volume, oxidative enzyme capacity, capillarity, and smaller muscle fiber sizes.
Symptoms and signs of low testosterone include decreasing lean body mass or skeletal muscle with increased body fat; fatigue, decreased energy, motivation and drive; decreased sex drive (libido) and erectile dysfunction; brain fog or reduced concentration or mental focus; mood changes including depression, anxiety or irritability; decreased bone density; and hair loss.
That one uh — has to do — actually that's the GART, but in — just in case, so your listeners know, GAMT has to do with Creatine, and so — you know — you can find yourself uh — get your skeletal muscles getting fatigued prematurely, or you might have trouble putting on uh — muscle mass.
Type IIB fibers are geared to generate ATP by anaerobic metabolic processes, however, they are not able to supply skeletal muscle fibres continuously with sufficient ATP, and fatigue easily.
Weak muscles or sudden fatigue in dogs, more technically referred to as Myasthenia gravis, is a syndrome that involves skeletal muscle weakness in the absence of obvious nervous system abnormalities.
Disruption of signal transmission within the NMJ resulting from presynaptic, synaptic, or post-synaptic defects causes congenital myasthenic syndromes (CMSs), heterogeneous neuromuscular disorders characterized by skeletal muscle weakness and fatigue.