Sentences with phrase «skeletal muscle stem cells»

A genetic approach in the mouse has been used to examine how skeletal muscle stem cells are born, and how they acquire their identity.

Further research will focus on generating skeletal muscle stem cells that can respond to continuous injury and regenerate new muscle long - term using the team's new isolation and maturation strategy.

Using mouse skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.

One of the molecular mysteries hindering development of regenerative therapy for muscles is uncovering the precise genetic and molecular processes that cause skeletal muscle stem cells (called myoblasts) to fuse and form the striated muscle fibers that allow movement.

«We learned a lot with this animal model, but perhaps the most important finding was what we observed when we transplanted skeletal muscle stem cells,» said Kyba.

The hamburger was grown in Post's lab using bovine skeletal muscle stem cells, collected from a piece of fresh beef.

The research of Dr Tajbakhsh focuses on identifying and characterising skeletal muscle stem cells.

Skeletal muscle stem cells unable to phosphorylate eIF2 exit quiescence, activate the myogenic program and differentiate, but do not self - renew.

Skeletal muscle stem cells propagated as myospheres display electrophysiological properties modulated by culture conditions.

For years, scientists have been trying different methods that direct human pluripotent stem cells to generate skeletal muscle stem cells that can function appropriately in living muscle and regenerate dystrophin - producing muscle fibers.

Claire Poulet (Ravens, TUD)-- «Electrophysiological properties of skeletal muscle stem cells: functional evidence of their potential for cardiac differentiation?»

But when even low doses of doxycycline were given to the recipients to turn on DUX4 in the skeletal muscle stem cells, muscle regeneration was severely impaired.

Manipulation of these genes in the mouse gives new insight into their role in the specification, proliferation and survival of skeletal muscle stem cells.