Using mouse
skeletal muscle stem cells as a model, we show that accumulating transcripts specifying the myogenic program are not translated in quiescent satellite cells, but are repressed by the action of microRNAs and RNA binding proteins.
Not exact matches
Specialized
stem cells known
as satellite
cells reside in
skeletal muscle in an inactive state.
The investigators found that when LIF - treated
muscle stem cells were transplanted to
skeletal muscle, they formed two to three times more
muscle fibers
as control
cells did.
Researchers at the University of Louisville have discovered a mechanism involved in
skeletal muscle repair that may enable clinicians to boost the effectiveness of adult
stem cell therapies for diseases such
as muscular dystrophy.
As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin — Madison has discovered a new way to make large concentrations of
skeletal muscle cells and
muscle progenitors from human
stem cells.
Skeletal muscle stem cells propagated
as myospheres display electrophysiological properties modulated by culture conditions.