Melanoma is a type of skin cancer that begins in
skin cells called melanocytes.
Researchers generally attribute tissue thickening (and ensuing damage to small blood vessels) to hyperactivation of
skin cells called fibroblasts.
Gallo's team has now discovered that injury stimulates
skin cells called keratinocytes, which surround the wound, to increase the production of vitamin D3 and that this in turn increases the expression of genes (CD14 and TLR2) that detect microbes.
JOE PALCA: Well, John, what they did was they - instead of starting with embryos and using those to derive embryonic stem cells, they started with skin cells, or actually precursors to
skin cells called fibroblast, that we all have in our skin.
Xu and his team, which includes researchers from Penn's departments of Dermatology and Biology, as well as the New Jersey Institute of Technology, started with human
skin cells called dermal fibroblasts.
For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary
skin cells called fibroblasts.
But mounting evidence implicates the immune system in the overproduction of cell - signalling molecules called cytokines, which stimulate
skin cells called keratinocytes to express genes that maintain an inflammatory microenvironment.
Fisher's goal was to understand how to strike down
the skin cells called melanocytes when they inexplicably go out of control and cause melanoma.
Not exact matches
The tattooing process works by injecting ink into the
skin, which stimulates an immune response in which
cells called «macrophages» move into the area and «eat up» the ink.
The OAR proposal uses a variation of therapeutic cloning
called altered nuclear transfer (ANT) in which the nucleus of a donor
cell (a
skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein
called nanog.
We referred to the news that these
cells,
called induced pluripotent stem
cells (iPSCs), could be made from human
skin....
This is because pumpkin contains a nutrient
called beta - carotene, which a form of vitamin A that helps improve eyesight and the health of
skin cells.
Papaya contains an enzyme
called papain that dissolves dead
skin cells — it is super effective and gentle.
These dots are
called «milia» and are caused from immature oil glands and dead
skin cells being trapped underneath your baby's
skin.
The substance on babies is
called vermix and contains the baby's
skin cells that it made and shed in the womb.
The outermost layer of the
skin having keratinized
cells is
called as stratum corneum.
This substance is
called meconium and is made up of things your baby ingested while in - utero, such as
skin cells, mucus and amniotic fluid.
In the direct reprogramming, the researchers exposed the adult
skin cells to a specific mix of signaling molecules the scientists» past research had found would convert healthy
skin cells directly into a type of brain
cell called medium spiny neurons, without intermediate steps along the way.
Seaweed derivatives, such as the phycocolloid
called «alginate,» made from the
cell walls of Macrocystis, have long been the emulsifying agent in
skin - care products.
Dr. Sharp and his colleagues had earlier discovered that an enzyme
called fidgetin - like 2 (FL2) puts the brakes on
skin cells as they migrate towards wounds to heal them.
These
cells,
called fibroblasts, help close wounds after
skin has been cut.
The idea fell out of favour following the scandal of 2005, and after the development of a way to turn ordinary
skin cells into so -
called induced pluripotent stem
cells (iPS
cells), which behave rather like hESCs.
Fat
cells called adipocytes are normally found in the
skin, but they're lost when wounds heal as scars.
Based on the little eyewitness information they could collect, Charlottesville police in 2003 started approaching dark -
skinned men with a request for what some
call get - lucky swabs — swipings from the inner cheeks of nonsuspects to collect
cells for DNA analysis.
These were surrounded by
skin - like
cells called fibroblasts, which form the heart's connective tissue.
A promising alternative to hESCs emerged in 2006 when researchers produced so -
called induced pluripotent stem
cells (iPS) from ordinary tissue such as
skin.
They also found that saliva contains another class of small RNAs,
called piwi - interacting RNAs, or piRNAs, which are produced by stem
cells,
skin cells and germ
cells.
The method,
called somatic
cell nuclear transfer (SCNT), replaces the DNA in an egg
cell's nucleus with the genetic material from the nucleus of a
skin cell, then tricks the egg
cell to start dividing as if it had been fertilized with sperm.
The enzyme,
called tankyrase, may prove useful for extending the lives of cultured
cells grown to repair burned
skin and other damaged tissue.
The study team removed fibroblasts (
skin cells) from DBA patients, and in
cell cultures, using proteins
called transcription factors, reprogrammed the
cells into iPSCs.
Scientists have known for a long time that sensory neurons
called TRPV1
cells can detect itchy substances on the
skin, says Mark Hoon, a neuroscientist at National Institute of Dental and Craniofacial Research in Bethesda, Maryland.
Skin - producing
cells called fibroblasts from the tip of an adult mouse's tail have been reprogrammed to make eggs, Japanese researchers report online October 17 in Nature.
Immune
cells called dendritic
cells educate T
cells, infection - fighting immune
cells, to smell the outer surface of the
skin and go there to do battle.
Another option is to take a
skin sample, culture
cells called fibroblasts and freeze them.
The latest research from the UCSB team shows that specialized
cells in the squid
skin called iridocytes contain deep pleats or invaginations of the
cell membrane extending deep into the body of the
cell.
Cells called neutrophils, which are considered the immune system's «first line of defense» because they react strongly to foreign invaders that enter the
skin through a cut or other injury, were also surprisingly important.
While the simple proteins
called histatins are well known for their ability to ward off infections, biochemist Menno Oudhoff of the University of Amsterdam discovered a subset of histatins that also prompt
cells from the
skin's surface,
called the epithelium, to close over a wound.
The team studied
skin cells,
called dermal fibroblasts, that help hair follicles develop, wounds heal, and generally maintain the structural integrity of
skin.
Through the use of powerful genomic techniques, researchers at the National Institute of Arthritis and Musculoskeletal and
Skin Diseases (NIAMS) have found that the development of immune
cells,
called innate lymphoid
cells (ILCs), gradually prepares these
cells for rapid response to infection.
Gage, Hetzer, Mertens and colleagues decided to try another approach, turning to an even newer technique that lets them directly convert
skin cells to neurons, creating what's
called an induced neuron.
But in a process
called asymmetric division, a
cell divides into two daughters that are not identical — a
skin stem
cell divides into another
skin stem
cell and a regular
skin cell, for example.
When susceptible people come into contact with flakes of cat
skin called dander, T
cells in their immune systems set off a chemical chain reaction that produces the familiar symptoms of allergy, including sneezing, runny noses, itching and asthma.
The researchers found that a protein
called KROX20, more commonly associated with nerve development, in this case turns on in
skin cells that become the hair shaft.
In the early 2000s, they injected mouse
skin cells with between four and seven pieces of protein
called transcription factors.
Using a process
called somatic
cell nuclear transfer (SCNT), a team from Oregon Health & Science University (O.H.S.U.) in Portland implanted the contents of individual
skin cells from adult male rhesus macaques into each of 304 macaque egg
cells stripped of their genetic material.
UNDER THE
SKIN Researchers have discovered mysterious structures, such as these bubblelike compartments
called vesicles that sit between the
cell membrane (cyan) and the
cell wall (purple) of the bacterium Halothiobacillus neapolitanus (cryotomogram, top; 3 - D reconstruction, bottom).
The enzyme,
called α - duronidase, will be produced in
skin cells taken from the babies themselves.
To do so, they converted
skin cells from patients into so
called induced pluripotent stem
cells.
Rattan joined the Clark group in 1984 and started exploring what happens when
skin, bone, and connective tissue
cells grow old and enter a state of limbo — called senescence — in which they neither divide nor die (see «More Than a Sum of Our Cells&raq
cells grow old and enter a state of limbo —
called senescence — in which they neither divide nor die (see «More Than a Sum of Our
Cells&raq
Cells»).
Melanoma is a cancer of the
skin cells that produce pigment,
called «melanin,» that produces color in our
skin.