Interestingly, we detected upregulation of p16 and p15 in Polycomb - null
skin epithelial stem cells in young mice where it is normally detected only in aged animals.
Not exact matches
The team's findings may also be relevant to inflammatory disorders that affect other parts of the body, such as the linings of the gut and bowel, which, like the
skin, are replenished by
epithelial stem cells.
The
epithelial stem cells, when implanted into immunocompromised mice, regenerated the different
cell types of human
skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.