Of the darker -
skin gene variants, three appear to have evolved from less pigmented variants.
Three of the darker -
skin gene variants appear to have evolved from variants linked with less pigment.
Not exact matches
The genetic shift introduced
variants for paler
skin and lighter - colored eyes;
genes for digesting lactose became common sometime later.
From the sequence data, they found
gene variants indicating that the man had dark
skin and eyes.
Their landmark findings will open the door to identify
gene variants controlling
skin microbiota and to define their link to various diseases such as
skin inflammatory disorders.
New genome - sequencing research suggests white European people with two copies of
variant forms of MC1R, a
gene linked to pale
skin and red hair, have faces that appear up to two years older than those who are the same age but don't have both copies.
We identify previously uncharacterized
genes and
variants associated with
skin pigmentation in ethnically diverse Africans.
When population geneticist Andrea Manica and graduate student Marcos Gallego Llorente at the University of Cambridge in the United Kingdom analyzed the sequence, they found that the Mota man had brown eyes and dark
skin, as well as three
gene variants associated with adaptation to high altitudes; some peaks in the highlands reach 4500 meters, as high as the Matterhorn.
While the dark
skin of some Pacific Islanders can be traced back to Africa,
gene variants from Eurasia also seem to have made their way back to Africa.
She had
gene variants that would have given her dark
skin, brown eyes, and brown hair, for example.
The team also found
variants of two neighboring
genes, HERC2 and OCA2, which are associated with light
skin, eyes, and hair in Europeans but arose in Africa; these
variants are ancient and common in the light -
skinned San people.
«Many of the
gene variants that cause light
skin in Europe have origins in Africa,» Tishkoff says.
A
variant within the DNA repair
gene XRCC3 is associated with the development of melanoma
skin cancer.
deCODE discovered the first
variant, a SNP called rs 401681, in its
gene discovery work on basal cell carcinoma (BCC), a common form of
skin cancer.
These folks carry two copies of a
variant of the MC1R
gene, which determines our hair and
skin color.
The
gene variants were linked to other signs of aging, such as thinning lips and sagging
skin along the jaw line, the researchers said.