Toxic Chemicals Caused Tumors, Not Capsaicin Researchers at The Hormel Institute, University of Minnesota, treated
the skin of mice with a mixture of DMBA (7,12 - dimetylbenz (a) anthracene), TPA (12 - O - tetradecanoylphorbol -13-acetate) and capsaicin.
Researchers at The Hormel Institute, University of Minnesota, treated
the skin of mice with a mixture of TPA and DMBA, two powerful and highly toxic tumor - producing chemicals.
Indeed, the very wavelengths that were most likely to generate oxygen free radicals were the wavelengths that do the most harm to
the skin of mice.
The skin of mice who got a strain with the compound remained largely normal (right).
A clue to this mystery came when Titze and his collaborators noticed an unusually high amount of sodium in the infected
skin of mice that had been bitten by cage mates.
A high - salt diet increased sodium accumulation in
the skin of mice, thereby boosting their immune response to a skin - infecting parasite.
They also showed that
the skin of mice with one copy of the mutation expressed about 60 percent the amount of KITLG as the skin of mice without the mutation.
They then implanted the engineered tissue scaffolds just under
the skin of mice with disabled immune systems.
Researchers from several institutions, including the University of Texas M. D. Anderson Cancer Center and Arizona State University, applied a potent skin cancer - causing agent found in cigarette smoke to
the skin of mice, some of which had been pretreated with avicins.
The scientists are currently trying to identify exactly where in
the skin of the mice the gene expresses itself.
«When we ablated the function of either of these proteins in
the skin of a mouse model system it had no obvious effect.
To figure out whether RASFs could spread arthritis from joint to joint, Neumann and her colleagues implanted human cartilage under
the skin of mice genetically engineered not to reject tissue from a different species.
The scientists also looked at how patterns of gene activity were changed in
the skins of the mice after treatment.
In this study, the researchers showed that the gels survived injection under
the skin of mice and successfully released two drugs, one hydrophobic and one hydrophilic, over several days.
The chemical, which they named lugdunin, inhibited S. aureus from growing in the petri dish, and when applied to
the skin of mice infected with S. aureus, it reduced or even eradicated the infection, the team reports today in Nature.
The team conducted investigations by grafting low - metastatic (LM) and high - metastatic (HM) melanoma tumour cells under
the skin of mice.
Two days after the nanosponge - hydrogel was injected underneath
the skin of a mouse, nearly 80 percent of the nanosponges were still found at the injection site.
The group, led by neurologist Rona Carroll of Harvard Medical School in Boston, found that injecting the capsules underneath
the skin of mice reduced the weight of tumors by 72 % in 3 weeks.
The team injected viruses into
the skin of the mice with or without the presence of a mosquito bite at the injection site and compared the reaction.
But the tissue does have blood vessels that proved functional when it was transplanted under
the skin of a mouse.
Howard Hughes Medical Institute (HHMI) researchers have isolated stem cells from
the skin of mice and shown that they have the power to self - renew and differentiate into skin and functioning hair...
Lymphoma, colon, and melanoma cancer cells were injected under
the skin of the mice.
To begin to decipher the pathogenic role of mast cells, St John et al. injected dengue virus under
the skin of the mouse ear.