Previous studies of
a skin pigmentation gene called MC1R had led many geneticists to think that dark skin colour — which is thought to protect against UV damage — is a fixed and consistent trait in all people of African descent.
Not exact matches
Another reason why a baby might have Heterochromia iridium or Heterochromia iridis is Waardenburg syndrome in which a
gene mutation occurs, causing changes in the
pigmentation levels of the hair, iris and
skin.
More than a hundred sites in the genome showed strong evidence of recent selection, including
genes that affect muscle tissue, hair, hearing, immune - system function,
skin pigmentation, sense of smell, and the body's response to heat stress.
We identify previously uncharacterized
genes and variants associated with
skin pigmentation in ethnically diverse Africans.
Variation in
pigmentation among human populations may reflect local adaptation to regional light environments, because dark
skin is more photoprotective, whereas pale
skin aids the production of vitamin D. Although
genes associated with
skin pigmentation have been identified in European populations, little is known about the genetic basis of
skin pigmentation in Africans.
The researchers also looked at the
gene expression of
skin cells from people with psoriasis and found decreased expression of the
genes involved in
pigmentation signaling, correlated with increased amounts of IL - 17 and TNF.
«Increased eye cancer risk linked to
pigmentation genes that dictate eye color: New research identifies genetic mechanisms behind rare form of melanoma are also associated with genetic risk for
skin melanoma.»
By working closely with the KhoeSan, a group of populations indigenous to southern Africa, the researchers have found that the genetics of
skin pigmentation become progressively complex as populations reside closer to the equator, with an increasing number of
genes — known and unknown — involved, each making a smaller overall contribution.
Approximately 15
genes have been directly associated with
skin pigmentation variation in humans, leading to its characterization as a relatively simple trait.
All these things like;
skin pigmentation, eye color, certain diseases are the result of our parent's
genes which present in our body.
In addition to affecting coat colors,
genes also control
pigmentation of the total body including the eyes and
skin as well as coat color.