Sentences with phrase «skin pigmentation in»

There can be increased facial skin pigmentation in pregnancy itself (without lupus) called Melasma, also known as chloasma or the mask of pregnancy.

Genetic determinants of hair, eye and skin pigmentation in Europeans Nat Genet [2007 Oct 21; [Epub ahead of print]-RSB-.

BCD02 has an effect on skin pigmentation in birds, with one form associated with white or grey skin, and another associated with yellow skin in well - fed chickens.

«MKTP surgery has long - term benefit for restoring skin pigmentation in vitiligo patients.»

A GWAS identified four genomic regions associated with skin pigmentation in Africa.

This study sheds light on the evolutionary history, and adaptive significance, of skin pigmentation in humans.

Analysis of the genetics of skin pigmentation in Africans informs upon melanocyte biology and the evolution of skin pigmentation in humans.

We observe extensive variation in skin pigmentation in Africa, with lowest melanin levels observed in southern African San hunter - gatherers and highest levels in East African Nilo - Saharan pastoralists.

Despite the wide range of skin pigmentation in humans, little is known about its genetic basis in global populations.

Variation in pigmentation among human populations may reflect local adaptation to regional light environments, because dark skin is more photoprotective, whereas pale skin aids the production of vitamin D. Although genes associated with skin pigmentation have been identified in European populations, little is known about the genetic basis of skin pigmentation in Africans.

We identify previously uncharacterized genes and variants associated with skin pigmentation in ethnically diverse Africans.

Being born without skin pigmentation in the U. S., a condition called albinism, does not usually shorten an individual's lifespan.

So concludes an analysis of skin pigmentation in people from several regions of Africa.

Not exact matches

From the fact that a person has a given shade of skin pigmentation no other fact of any consequence can bee inferred, except that he will be accorded a certain kind of treatment by people in a race - conscious society.

We are one species with a range of variability in the amount of pigmentation in our skin, and the extent to which sun exposure has darkened it.

Average height, occurance of body hair, skin pigmentation, ability to process certain foods - all have notably changed even in just the last few thousand years of recorded history, and very depending on location and populations.

In 1968 he recanted his earlier statements and preached a well - publicized sermon on «The Church of the Open Door»: «I have come to the profound conclusion,» he said, «that to separate the Body of Christ on the basis of skin pigmentation is unthinkable, unchristian, and unacceptable to God.»

In the evening I cleanse and exfoliate with Beauty Counter's Charcoal Cleansing Bar and the Clarisonic skin brush then moisturize with grapeseed oil and Living Libations Dew Dab which helps prevent breakouts and combat hyper pigmentation.

In addition to that, the hormone that regulates skin pigmentation (melanocyte - stimulating hormone) also increases.

Another reason why a baby might have Heterochromia iridium or Heterochromia iridis is Waardenburg syndrome in which a gene mutation occurs, causing changes in the pigmentation levels of the hair, iris and skin.

Side effects of chemical peels include swelling, crusting, reddening, acne, and pigmentation changes in the skin.

Together, these sites account for about 30 per cent of the variation they found in skin pigmentation among the volunteers.

The combined data allowed the team to find eight sites in the human genome that are particularly associated with the level of skin pigmentation.

Previous studies of a skin pigmentation gene called MC1R had led many geneticists to think that dark skin colour — which is thought to protect against UV damage — is a fixed and consistent trait in all people of African descent.

Albinism is a genetic disease causing partial or complete loss of pigmentation, or coloring, in the skin, eyes and hair.

Changes to skin pigmentation pathways probably reflect selective pressures related to sunlight exposure that humans experienced as they spread out from humanity's origins in Africa to other parts of the world and adapted to local environments.

More than a hundred sites in the genome showed strong evidence of recent selection, including genes that affect muscle tissue, hair, hearing, immune - system function, skin pigmentation, sense of smell, and the body's response to heat stress.

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening.

A genome - wide association study (GWAS) of 1570 Africans identified variants significantly associated with skin pigmentation, which clustered in four genomic regions that together account for almost 30 % of the phenotypic variation.

Individuals with darker pigmentation — in particular people with African, Hispanic or South - Asian genetic background — are more likely to develop this skin tissue disorder.

The discovery sheds new light on our understanding of the genetic complexity underpinning variations in human pigmentation, and could advance our knowledge of conditions linked to pigmentation, such as skin, testicular, prostate and ovarian cancers.

Examining ethnically diverse African genomes, we identify variants in or near SLC24A5, MFSD12, DDB1, TMEM138, OCA2, and HERC2 that are significantly associated with skin pigmentation.

Co-author Dr. David Hinds from 23andMe said: «While the genetics of hair colour is an interesting problem in itself, we hope that better understanding of the biology of melanin pigmentation will be applicable to studies of diseases that interact with pigmentation, such as skin cancer or vitiligo.»

These variants arose independently from eye and skin pigmentation — associated variants in non-Africans.

«We've been trying to track down the genetic and molecular basis of naturally occurring traits — such as hair and skin pigmentation — in fish and humans to get insight into the general principles by which traits evolve,» said David Kingsley, PhD, professor of developmental biology.

The researchers also looked at the gene expression of skin cells from people with psoriasis and found decreased expression of the genes involved in pigmentation signaling, correlated with increased amounts of IL - 17 and TNF.

A new study supported by the Milstein Medical Research Program at The Rockefeller University, however, has uncovered the molecular roots of skin discoloration that is often associated with psoriasis, suggesting the possibility of new treatments for pigmentation changes seen not only in psoriasis, but also in other conditions such as eczema and acne.

Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians.

iSAFE identified identical mutations in multiple non-African populations in 5 regions associated with skin pigmentation, suggesting an early response to the onset of selection as humans migrated out of Africa.

In people with vitiligo, which causes patchy loss of pigmentation, a certain kind of T cell is dominant in the afflicted areas of skin; patients with psoriasis, on the other hand, exhibit an increase in another kind of T celIn people with vitiligo, which causes patchy loss of pigmentation, a certain kind of T cell is dominant in the afflicted areas of skin; patients with psoriasis, on the other hand, exhibit an increase in another kind of T celin the afflicted areas of skin; patients with psoriasis, on the other hand, exhibit an increase in another kind of T celin another kind of T cell.

She adds, «Just 15 minutes of sunlight in the summer produces about 3000 international units of vitamin D depending on latitude and skin pigmentation, which is equivalent to 30 glasses of milk.

«Our aim with this project was to use this method to demonstrate the feasibility of making 3D in - vitro pigmented human skin constructs, with uniform skin pigmentation.»

A new method for controlling pigmentation in fabricated human skin has been developed by researchers from A * STAR's Singapore Institute of Manufacturing Technology (SIMTech) and the Singapore Centre for 3D Printing (SC3DP) at Nanyang Technological University.

«Skin pigmentation is far more genetically complex than previously thought: By studying an African population underrepresented in most datasets, researchers find genetic complexity of pigmentation varies by latitude.»

In a retrospective study, researchers found that a majority of areas of the skin treated with surgery still had «very good to excellent» color match pigmentation five years later.

In their paper, publishing today in Biofabrication, the team show how they utilise 3D bioprinting to control the distribution of melanin - producing skin cells (melanocytes) on a biomimetic tissue substrate, to produce human - like skin pigmentatioIn their paper, publishing today in Biofabrication, the team show how they utilise 3D bioprinting to control the distribution of melanin - producing skin cells (melanocytes) on a biomimetic tissue substrate, to produce human - like skin pigmentatioin Biofabrication, the team show how they utilise 3D bioprinting to control the distribution of melanin - producing skin cells (melanocytes) on a biomimetic tissue substrate, to produce human - like skin pigmentation.

TYRP1 is known to be involved in skin and hair pigmentation in several species.

Those markers can tell the story of human adaptation as early man moved from equatorial Africa into lower - light regions, and may explain changes in skin pigmentation to metabolize more sunlight, or how indoor living has silently damaged human health.

It could be an albino, lacking in any skin pigmentation.

Treatment of melanised epidermis with alpha - melanocyte stimulating hormone (αMSH), a physiological agent that controls skin pigmentation, activated the production of melanin in the tissue.