Not exact matches
In
skin tumors the process can start with a change in a single
gene, such as H - ras.
Myc is a proto - oncogene or master cancer
gene that spurs
tumor growth in a variety of cancers including breast, lung, colon, brain,
skin, leukemia, prostate, pancreas, stomach and bladder.
«Surprising role of
gene regulator protein in development of
skin tumors.»
The authors uncover the cellular and molecular mechanisms, as well as the
gene network regulated by Sox9 during the early steps of
skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.
But now geneticists at the University of Geneva (UNIGE), Switzerland, sequenced the DNA of these
skin tumors, in order to determine the
genes that are responsible for the cancerogenesis.
They've used a gun powered by pressurized helium to fire microscopic gold bullets, coated with
genes, into
skin cells surrounding
tumors in mice.
And when viruses containing the four
genes insert themselves into the genomes of
skin cells, they can activate innate cancer
genes and cause
tumors.
The analysis of 278 transposition - induced prostate, breast and
skin tumors detected tissue - specific and shared data sets of known and candidate
genes involved in cancer.