It restored normal blood sugar and insulin levels in animals that already had diabetes and prevented or
slowed its onset in young mice that had not yet developed the disease.
Not exact matches
This may partly explain why real wage growth has not significantly declined since the
onset of the recession
in December 2007 and why hiring has been
slow since the start of the recovery
in mid-2009.
There are many different types of changes
in an ambient environment — some very fast like electromagnetic waves, some very
slow like the accumulation of pollutants
in the air, and some with rapid
onsets and offsets but long durations like rainfall.
More importantly, the reality that virtually every natural system essential to The Big Economy was
in a state of
slow degradation at century's end was not the reality at century's
onset.
Lets avoid stating
slow at all cost, when Lpool are threatened from the
onset they can really be poor but once they have there noses
in front as seen
in the City game then you are
in trouble.
The
onset of a long period
in opposition for social democratic standard - bearers such as Labour
in Britain and the SPD
in Germany, coupled with continuing
slow growth, high unemployment and falling unionisation, led the parties of the Socialist International into a comprehensive accommodation with neo-liberalism — albeit one wrapped
in soothing social market rhetoric and homeopathic concessions at the margins.
A few drugs have shown promise
in cell culture or animal models, but clinical trials
in humans are time consuming because of the
slow onset and progression of the disorder's clinical symptoms.
In the Science paper, the researchers derived a quantity related to the fault's
slow onset, called the slip weakening distance, and found it to be several orders of magnitude higher that laboratory experiments on rock samples would predict.
The drug targets a specific cellular process that occurs
in animals, including humans, delaying the
onset of age - related deaths by
slowing the aging process.
An extended minimum occurs whenever the plasma moves quickly at the beginning of a cycle — preventing a large buildup of magnetic fields — but then
slows down toward the end, delaying the
onset of the next cycle, the team reports online today
in Nature.
Many clinical trials have since focused on trying to
slow disease
onset in these individuals.
One study even identified two genes
in which particular variants can
slow the
onset of AIDS, demonstrating the potential of this approach for understanding why people vary
in their susceptibility to infectious diseases.
«We continue to believe that mechanisms that combat aging
in caloric restriction will offer a lead into drugs or other treatments to
slow the
onset of disease and death.»
As for therapeutics, Xavier, who is also the Kurt Isselbacher Chair
in Medicine at Harvard Medical School and Co-Director of the Center for Microbiome Informatics and Therapeutics at MIT, says that knowing which species are absent and which are flourishing
in the gastrointestinal tract of children with T1D may help make it possible to
slow progression of the disease after
onset by revealing ways to manipulate the microbiome and,
in turn, microbiome - induced immunoregulation.
«Imagine what you would do
in your early 40s to
slow the
onset of the disease.
If you can predict the disease you may be
in a position to
slow down its
onset and progression through therapeutic interventions.
Diagnosed with
in a very rare early -
onset,
slow - progressing form of Amyotrophic lateral sclerosis (ALS; also known as motor neurone disease or MND)
in 1963 at age 21, he was gradually left him wheel chair bound.
When the UCSD researchers isolated and shut off mutant SOD1genes
in the motor neuron cells only, the disease
onset slowed, but the course of the disease eventually caught up to the control rodents.
Behaviorally, the mice with 110 CAG repeats showed a sharp decline
in both rotarod and open field performance from around 4 weeks of age whereas the 240 CAG repeat mice displayed a 2 - 3 week delay
in the
onset of behavioral decline with a much
slower progression of decline
in both tasks as compared to 110 CAG repeat counterparts.
A humanized TNF transgenic mouse overexpressing human TNF resulting
in the spontaneous development of late
onset,
slow progression, long lasting arthritis more closely resembling adult
onset of human rheumatoid arthritis.
The findings demonstrate similarities
in progressive muscle weakness and a decline
in motor coordination
in both models of motor neuron disease with a later
onset and
slower progression noted with PFN1 animals.
Slow -
onset adaptive changes that arise from sustained antidepressant treatment, such as enhanced adult hippocampal neurogenesis and increased trophic factor expression, play a key role
in the
Every year we are getting closer to identifying treatments that could
slow down the disease process, and ways to prevent or delay disease
onset in HD gene carriers» Professor Sarah Tabrizi
If people who take aspirin have a later age of
onset of HD symptoms, or a
slower disease course, we could guess that the immune reaction observed
in HD patients is a bad thing.
And
in animal studies using mice with HD, research has shown that «environmental enrichment» - giving the mice more stimulating surroundings - delays the
onset and
slows the progression of the disease.
There are currently no disease - modifying treatments that have been shown to
slow the progression or delay the
onset of HD
in humans; however, several compounds have demonstrated promise
in animal models of HD.1 Robust and sensitive markers of disease progression are required to assess their efficacy
in humans.
These changes could lead to
slower metabolism, greater difficulty controlling blood sugar and a faster
onset of disability, according to the authors of the study, published April 18
in the journal Diabetologia.
The addition of flaxseed
slowed the
onset of type 2 diabetes
in animal studies as well as protecting kidneys from the usual damage as a result of diabetes.
Keep
in mind, perimenopause means «around menopause,» so it could usually be described as a
slow, steady march toward the end of estrogen production that commonly presents as a very gradual
onset of the menopausal symptoms we listed above.
Anti-aging therapy focuses on the science of aging and uses the latest
in scientific advancements to stabilize hormone fluctuations, to
slow down the
onset of chronic disease and to restore optimal health and vitality
in any way possible.
AS typically has a
slow onset, and we set up an appointment
in another 6 weeks for follow up.
Simply stressing the same energy system over and over again not only results
in a single - speed endurance athlete who can't go fast when it matters and never goes
slow enough for recovery, but may also result
in more rapid
onset of overuse injury from repeated stress on the same joints.
Gluten intolerance is more difficult to diagnose
in a patient, it has a
slower onset than CD and may be much more difficulty to pick up due to the vague and broad range of symptoms some patients present with.
Alzheimer's disease Studies on arachidonic acid and the pathogenesis of Alzheimer's disease is mixed with one study of AA and its metabolites suggests they are associated with the
onset of Alzheimer's disease, [18] whereas another study suggests that the supplementation of arachidonic acid during the early stages of this disease may actually be effective
in reducing symptoms and
slowing the disease progress.
However, the sets are
slow in the sense that one set of 5 reps, or 15 seconds, is interspersed with a long rest, say 1 hour, before the
onset of the next set.
These conditions are very real concerns for females, and while menopause is often a time when we start to notice a decline
in memory and bone density, the
onset of these changes happens years earlier as growth hormone production begins to
slow down.
A study conducted by the Institute for Basic Research
in Developmental Disabilities
in New York showed that walnuts can improve memory deficits and learning skills and may also have a beneficial effect
in reducing the risk, delaying the
onset, and
slowing the progression of Alzheimer's disease.
It's
in his determination to care for her at home by himself when her funny turn — it seems like it must have been a stroke, though there's also hints of rapid -
onset Alzheimer's, too — becomes a
slow deterioration, mentally and physically, toward the inevitable.
The Michelin engineers monitor the pressure
in the tyre constantly, mainly to detect the
onset of a
slow puncture — a major safety hazard at a high - speed circuit like Le Mans.
The recommended treatment for anal gland tumors is complete surgical excision followed by chemotherapy (e.g. carboplatin or mitoxantrone)
in order to prevent or
slow the
onset of metastasis.
The
onset of clinical signs may appear suddenly but,
in general, is a
slow progression.
Signs of chronic liver disease are similar to acute liver disease but are
slower in onset and may appear gradually over the period of several months; weight loss, increased thirst, and increased urination may also indicate chronic liver problems.
In some cases, if the absorption of xylitol is slowed down, as when a dog ingests chewing gum meant for people, the onset of hypoglycemia in the dog may be delayed up to 12 hour
In some cases, if the absorption of xylitol is
slowed down, as when a dog ingests chewing gum meant for people, the
onset of hypoglycemia
in the dog may be delayed up to 12 hour
in the dog may be delayed up to 12 hours.
When Jessica Morgan, a curator with the Tate Modern discovered her art
in 2009, Ms. Choucair had finally stopped her work, which had started to
slow about a decade earlier with the
onset of Alzheimer's disease.
The screening showed that the activities planned would generate climate benefits
in terms of adaptation to
slow -
onset climate change (60 %), adaptation to extreme events (18 %) and climate change mitigation (19 %).
People are already experiencing the impacts of climate change through
slow onset changes, for example sea level rise and greater variability
in the seasonality of rainfall, and through extreme weather events, particularly extremes of heat, rainfall and coastal storm surges.
«For example, there was a call coming out on
slow -
onset events, which,
in the UNFCCC language, means sea - level rise, glacial retreat, ocean acidification, desertification.
Slow onset events are mentioned
in the Cancun Agreements with a footnote saying that these are events «including sea level rise, increasing temperatures, glacial retreat and related impacts, salinization, land and forest degradation, loss of biodiversity, and desertification».
Donors and national governments should put multi-hazard early warning systems
in place to alert officials to both
slow - and rapid -
onset disasters, as well as epidemics, before they reach full emergency levels.
What's happening
in Berlin, Alaska is what climate scientists describe as
slow -
onset climate change event, such as sea level rise or ocean acidification.