Sentences with phrase «slows growth of these cells»

PTEN is known as a tumour suppressor gene meaning that it typically slows the growth of cells and its loss can lead to cancer.

The American Cancer Society: In a published report states that ellagic acid supplements may slow the growth of some cell abnormalities.

Not exact matches

Meanwhile, Techcrunch notes that although mobile subscriber growth in China is actually slowing — since most people have cell phones — the percentage of people who can connect to the Internet on their phones is accelerating rapidly.

The pigment that makes the potato purple — anthocyanin — has been found to slow down the growth of cancerous cells.

As well as containing vitamins and minerals its abundant with polyphenol antioxidants which help protect against cancer, one polyphenol in particular can slow or halt the growth of cancer cells!

The phase 3 study, published online in The Lancet, is the latest to show the effectiveness of everolimus in slowing the cell growth that is overactive in patients with TSC.

Lo's team set out to find ways to further weaken the tumors, since the drug addiction response (which can range from a mere slow down of the cancer's growth rate to cancer cell death), can be used to improve clinical outcomes.

The team led by Andreas Plückthun, Director of the Department of Biochemistry at the University of Zurich, involving postdoc Rastik Tamaskovic and PhD student Martin Schwill, has now found out why these antibodies merely slow tumor growth rather than killing off the cancer cells.

In addition to diminishing the tumor's energy supply, the diet slows the growth of glioblastoma cells by altering a cellular - signaling pathway that commonly occurs in cancers, according to the researchers.

A study analyzing brain tumor genomics on a single - cell level has found evidence that cancer stem cells fuel the growth of oligodendrogliomas, a slow - growing but incurable form of brain cancer.

One medication in particular is bevacizumab, a drug used to treat advanced cancers that slows the growth of new blood cells.

Isoflavones have been shown to slow the growth of breast cancer cells in laboratory studies, and epidemiological analyses in East Asian women with breast cancer found links between higher isoflavone intake and reduced mortality.

The tumors» recruitment of these inflammatory cells thus enabled them to resist what would otherwise have been a deadly dose of radiation, so that their growth slowed only modestly compared to control mice that had received no radiation.

The rub was if algae are deprived of nitrogen, the cells become stressed and begin to produce lipids, but their growth rate slows.

Inhibiting ALDH1A3 - mediated pathways slows the growth of mesenchymal glioma stem cells and might provide a promising therapeutic approach for glioblastomas with a mesenchymal signature.

Anti-cancer drugs called mTOR inhibitors slow the growth of cancer cells but show limited ability to cause cancer cell death.

The study published in Cell Death and Disease showed that aspirin slows down the growth of mesothelioma by blocking the carcinogenic effects of the inflammatory molecule, High - Mobility Group Box 1 (HMGB1).

The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.

When the researchers reduced the amount of IL13RA2 expression in the cancer cells, they found that the tumor growth was significantly slower in models.

The professor and his colleagues demonstrated in their study that while resistance to drugs like chloroquine, which works to slow the growth of malaria, has been explored, an explanation of the resistance to the cell - destroying effects of the medication has not been fully understood.

By blocking these in lung endothelial cells, the researchers were able to slow lung tumor growth in mice and also reduce the spread of metastatic tumors.

Although the H3K27M mutation disrupts a different chemical tagging system, the scientists showed that panobinostat slowed the growth of a line of cells that had the mutation.

When the team blocked the activity of L1CAM in cultured human colon cancer cells, the cells» growth slowed dramatically.

If this modification of the protein entry gate can no longer take place, the process of cell division — and ultimately also growth — is slowed down.

«But we now know that when DAZAP1 is overexpressed, the growth of cancer cells slows down significantly.

Drugs like fluorouracil, oxaliplatin and irinotecan work by mimicking and damaging DNA molecules, or inhibiting enzymes involved in cell and DNA replication, slowing the uncontrolled growth of tumor cells.

Through a variety of preclinical experiments, the team demonstrated that increasing the expression of miR - 184 slows the growth and invasive characteristics of glioma cells through direct regulation of SND1.

In the cold seep worm, the cells at the edges of the trophosome die at about the rate that new cells are produced, slowing the worm's growth and keeping the worm stocked with young cells.

In particular, consumption of whole plant foods slows digestion and provides higher amounts and a more favourable balance of essential and vital nutrients per unit of energy; resulting in better management of cell growth, maintenance, and mitosis (cell division) as well as regulation of blood glucose and appetite.

The research found that filaments of CrvA assemble on one side of a V. cholerae bacterium, forming a hard polymer that slows growth on that side of the cell.

The test drug slowed the growth of kidney cysts in two mouse models and in cell cultures of human kidney cysts, the study showed.

Nine months later, cell growth had shown no signs of slowing down.

A more alkaline growth medium, for example, made the autoinducer less stable, slowing activation of the cell - suicide gene and increasing the population.

When antibodies and other methods were used to dramatically deplete the supply of Tregs in mice, the researchers saw a dramatic jump in the numbers of activated dendritic cells and CD8 + T cells in pancreatic tumor tissue, as well as a slowing of tumor growth.

In 1997, molecular biologist Chi Dang of Johns Hopkins Medical School in Baltimore, Maryland, found that blocking one enzyme involved in glycolysis, lactate dehydrogenase A (LDH - A), could slow the growth of cancer cells in petri dishes.

Additionally the researchers think that targeting CRIPTO and GRP78 — which are ideal drug targets since they are present outside of cells — could halt or slow cancer growth.

They showed that it slowed the growth of human lung cancer cells but not kidney cancer cells in these mice.

«Inhibition of the EZH2 pathway slows growth of tumors in mouse brain derived from glioma stem cells from the enhancing margin of human tumors.

Another lab ran into a similar problem when it tried to replicate work by Stanford stem cell biologist Irving Weissman and his colleagues, who reported in 2012 in the Proceedings of the National Academy of Sciences that an antibody to a tumor cell surface receptor called CD47 can slow tumor growth in mice.

Decorin is a protein that is part of connective tissue like bone, but that also plays a signaling role, interacting with growth factors to slow the rate that cells divide and multiply, unless turned off by too much p53.

The findings, which follow Dana - Farber scientists» recent discovery that CDK4 / 6 inhibitors can slow the growth of cancer cells carrying a surplus of a certain protein, suggest that the drugs» potential in cancer treatment has only begun to be tapped.

Using genetic techniques to knock out PBK slowed the growth of the group's adrenal cancer cell lines.

The team used a combination of experiments to zero in on the molecular activity of melittin at the «minimal inhibitory concentration» (MIC), the lowest concentration that's been shown to slow the growth of target cell populations.

Bradner and Mitsiades had reported in Cell in 2011 that the inhibitor blocks the Myc cancer gene and thereby slows the growth of multiple myeloma tumors in mice.

Stents coated with a drug that activates SHP - 1, and thus slows the accelerated growth of these vascular cells, might help in treating arterial disease in diabetes, says King, who is also Professor of Medicine at Harvard Medical School.

Knowing that insulin can stimulate the growth of blood vessels, «our expectation was that knocking out insulin signaling in these cells might slow the growth of blood vessels and reduce tumor formation in these mice,» Rask - Madsen says.

In another experiment, treating human brain cancer cells containing FGFR3 - TACC3 with mitochondrial inhibitors interrupted the production of energy inside cancer cells and significantly slowed tumor growth.

Mebendazole potently inhibited hedgehog (Hh) signaling and slowed the growth of Hh - driven human medulloblastoma cells at clinically attainable concentrations [27].

(Fludara) An antineoplastic agent, this medicine works by slowing or stopping the growth of cancer cells.

The same chemical compound was previously shown to slow the growth of ovarian cancer cells, researchers say.