Sentences with phrase «small cell lung cancer»

Further analysis showed some of the activated genes were enriched in small cell lung cancer and other cancer - promoting pathways.

The team investigated the sensitivity of small cell lung cancer cells to AZD3965 and showed that in those cells lacking an alternate lactate transporter, MCT4, the drug had an effect.

«Our laboratory results are promising and certainly provide encouragement to test this treatment clinically in patients with small cell lung cancer.»

Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c - Kit in small cell lung cancer cells.

Dr. Weiss» study of pembrolizumab was presented during a session on small cell lung cancer when the theme of the conference was Science Drives Lung Cancer Advances.

Jacks» lab is now investigating the roles of genes associated with other types of lung cancer, such as small cell lung cancer.

Approximately one year after successful treatment with cytotoxic chemotherapy and radiotherapy, patients with advanced Small Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further chemotherapy.

One, in which Dr. Weiss was the senior author, highlighted the extended survival of metastatic small cell lung cancer (SCLC) patients who received statins.

«Cause of chemoresistance in small cell lung cancer discovered.»

That prospect looked even more remote when Martensen's doctors discovered that he had squamous small cell lung cancer, a less common form in which the cancer cells are scaly and thin.

Manchester scientists have shown that a new drug could prove useful in treating small cell lung cancer — the most aggressive form of lung cancer.

Smokers who have chronic obstructive pulmonary disorder (COPD) may face nearly twice the risk of getting small cell lung cancer (SCLC)-- the deadliest form of lung cancer — than smokers who don't have COPD, according to a large worldwide study led by researchers at the Harvard T.H. Chan School of Public Health.

Novel hybrid phenotype revealed in Small Cell Lung Cancer by a transcription factor network model that can explain tumor heterogeneity.

Li RJ, Zhao LJ, Zhan ZL, Lu X, Gong LL, Wang P. [Significance of expression of chemokine receptor and matrix metalloproteinase in small cell lung cancer].

CXCR4 / CXCL12 Axis in Non Small Cell Lung Cancer (NSCLC) Pathologic Roles and Therapeutic Potential Ori Wald, Oz M. Shapira, Uzi Izhar Theranostics 2013; 3 (1): 26 - 33.

Lung pathology experiences a paradigm shift moving from previously oversimplified two - part classification of nonsmall cell lung cancer and small cell lung cancer variants to a highly complex description of the biological variety of this tumour type.

Scientists from the Cancer Research UK Manchester Institute, based at The University of Manchester and part of the Manchester Cancer Research Centre, teamed up with experts at AstraZeneca, as part of a collaboration agreed in 2010, to test a drug — known as AZD3965 — on small cell lung cancer cells.

«We found that the combination of pembrolizumab and chemotherapies evaluated thus far — in patients with advanced small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC)-- appears to be safe,» said Dr. Glen Weiss, Director of Clinical Research and Medical Oncologist at CTCA ® at Western, where he currently supervises more than 30 clinical trials involving hundreds of patients.

The abstract title was: Attempt to Validate Drug Repositioning for Metastatic Small Cell Lung Cancer (SCLC) Therapy Identifies Statins Associated with Survival Benefit.?

The Salk scientists now hope to develop a mouse model of small cell lung cancer, a more aggressive form of the disease that's been linked to smoking.

Embryo Gene Linked to Lethal Lung Cancer A multi-institutional and comprehensive study, led by Kimmel Cancer Center investigators, revealed genetic mutations linked to a lethal type of lung cancer, known as small cell lung cancer (SCLC).

This new drug — AZD3965 — is currently in clinical trials, but it has not yet been tested in small cell lung cancer.»

Non — small cell lung cancer may involve genetic aberrations that can be used to direct therapy.

A late breaking subanalysis of the phase III CONVERT trial presented at the European Lung Cancer Conference (ELCC) shows that white blood cell boosting drugs are safe during concurrent chemo - radiotherapy of small cell lung cancer (SCLC).

15 % of people with lung cancer have Small Cell Lung Cancer.

Professor Caroline Dive, who led the research, said: «Small cell lung cancer has a dismal prognosis and we have seen little improvement in treatment for many years.

The Genes and Cancer Group at the Cancer Epigenetics and Biology Program of the IDIBELL has found that the MAX gene, which encodes a partner of the MYC oncogene, is genetically inactivated in small cell lung cancer.

Our expert lung cancer team works together to care for all types of cancer that affect the lungs and chest, including non-small cell lung cancer, small cell lung cancer, mesothelioma, and thymoma.

Sarah B. Goldberg, MD, MPH, an assistant professor of medicine at the Yale School of Medicine and Yale Cancer Center, discusses osimertinib (Tagrisso) for the treatment of patients with non — small cell lung cancer.

A Phase 1/2 Study on the Safety of Rovalpituzumab Tesirine Administered in Combination with Nivolumab or Nivolumab and Ipilimumab for Adults with Extensive - Stage Small Cell Lung Cancer

Small Cell Lung Cancer (SCLC): Overexpression of CXCR4 is found in SCLC [30, 31, 37] and mediates the migration of SCLC to bone marrow along an SDF - 1 gradient [37].

In men, adenocarcinoma was the most common type (42 %), followed by squamous cell carcinoma (35 %), small cell lung cancer (18 %), and others (5 %).

We investigated its putative effects on small cell lung cancer (SCLC) circulating tumor cell (CTC) cell lines which are operative in metastasis and exhibit a phenotype overlapping with CSCs [Hamilton, manuscript submitted].

And, around 14 percent of all lung cancer cases are small cell lung cancer (SCLC).

Verma has successfully developed lentiviral vector - mediated mouse models for glioblastoma, lung adenocarcinoma and small cell lung cancer (SCLC).