Open Source drug discovery projects for tropical diseases We develop methods for comparative docking of
small chemical compounds and their target proteins.
Not exact matches
On the extremely
small scale, however, the push and pull of electrons and protons is what controls
chemical reactions, including every
compound and every process in your body.
In the heyday of antibiotic development in the mid-20th century many different
chemical compounds with antibacterial properties were examined, but only a
small proportion were selected for development into drugs.
Using just one tropical plant called a bromeliad, scientists were able to remove 80 % of six different
compounds from the air in a
small, sealed container, they reported today at the American
Chemical Society's annual meeting.
«I have developed methods for
chemical analysis that for the first time make it possible to identify fragrance
compounds that have been exposed to air and thus become potent allergens in
small amounts and that people may come in contact with in consumer products,» says Johanna Rudbäck at the Department of Chemistry and Molecular Biology, University of Gothenburg.
Confronted with these findings, scientists began to wonder whether
small quantities of synthetic
chemical compounds found in our food and water — and in everyday products like makeup, plastics, and bug spray — could be sabotaging human fertility, undermining our immune systems, or affecting prenatal development.
These
small molecules, and their improved
chemical daughter
compounds in the future, will help discovery of novel epitranscriptomic mechanisms regulating physiological and pathophysiological processes.
The
small size of the fish allows for economic testing of large
chemical libraries and combinations of
compounds in a scale unfeasible for mammal testing.
The emerging field of DNA - encoded
chemical library allows us to perform selection of
small molecule
compounds.
Already, he knows that most IBD patients have a far
smaller range of microbial species in their guts, compared to healthy people Stool transfers help restore that diversity and all the possibly beneficial
chemical compounds that those microbes release into our bodies.
Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas using the approaches of a field called
chemical biology, which is using
small molecules —
chemicals — to probe biological systems in the hopes of developing
compounds that could be new drugs.
This is basically tweaking the molecules: making
small chemical changes to the
compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.
This is a
chemical compound produced by the stomach which tags onto vitamin B12 released from protein in the stomach and carries it down the intestine to allow B12 to be absorbed in the lower part of the
small intestine.
Silymarin is one of a
small number of
compounds able to cross the blood - brain barrier and affect neural function and
chemical neurotransmitters.
Recalling the concern reflected in the outcome document of the United Nations Conference on Sustainable Development, entitled «The future we want», 1 that the health of oceans and marine biodiversity are negatively affected by marine pollution, including marine debris, especially plastic, persistent organic pollutants, heavy metals and nitrogen - based
compounds, from numerous marine and land - based sources, and the commitment to take action to significantly reduce the incidence and impacts of such pollution on marine ecosystems, Noting the international action being taken to promote the sound management of
chemicals throughout their life cycle and waste in ways that lead to the prevention and minimization of significant adverse effects on human health and the environment, Recalling the Manila Declaration on Furthering the Implementation of the Global Programme of Action for the Protection of the Marine Environment from Land - based Activities adopted by the Third Intergovernmental Review Meeting on the Implementation of the Global Programme of Action for the Protection of the Marine Environment from Land - based Activities, which highlighted the relevance of the Honolulu Strategy and the Honolulu Commitment and recommended the establishment of a global partnership on marine litter, Taking note of the decisions adopted by the eleventh Conference of the Parties to the Convention on Biological Diversity on addressing the impacts of marine debris on marine and coastal biodiversity, Recalling that the General Assembly declared 2014 the International Year of
Small Island Developing States and that such States have identified waste management among their priorities for action, Noting with concern the serious impact which marine litter, including plastics stemming from land and sea - based sources, can have on the marine environment, marine ecosystem services, marine natural resources, fisheries, tourism and the economy, as well as the potential risks to human health; 1.
Modified genes, expression vectors, probes, modified proteins, monoclonal antibodies and receptors, cells and other
chemical compounds such as
small organic molecules are patentable.