Sentences with phrase «small deletions»

«I saw a relatively small deletion in the X chromosome, identified as Xp11.22; it had only a few genes in it.

When genetic messages get jumbled with small deletions like this, cells have machinery for recognizing the errors and ignoring their contents.

SV40 mutants with small deletions or base substitutions have been isolated by in vitro site - specific or random local mutagenesis of recombinant DNA followed by cloning in E. coli.

The human UFD1L gene was deleted in all 182 patients studied with 22q11 deletion, and a smaller deletion of approximately 20 kilobases that removed exons 1 to 3 ofUFD1L was found in one individual with features typical of 22q11 deletion syndrome.

Dr Siddharth Banka, Clinical Senior Lecturer at the Manchester Centre for Genomic Medicine, who led the study, explained: «Our team has identified that this new syndrome is caused by a small deletion on chromosome 6 that affects the function of hypothalamus, a region of the brain that plays a number of important roles in the body.»

The syndrome is caused by a small deletion on chromosome 22.

As Calderón explains, this gene is present in the X chromosome and in the Y chromosome however, there is a small deletion — a special type of chromosomal anomaly — in X, which makes it ideal for sex determination by DNA amplification.

«The most common mutation was a small deletion within the NFKBIE gene.

DNA sequencing further showed that these cell colonies included some small deletions in the MSTN gene (Figure 2B).

DNA sequencing of three quadruple - mutant colonies further confirmed that small deletions were present in all eight alleles of four genes (Figure 2F).

DNA sequencing further confirmed that some small deletions and insertions (indels) were introduced into the gRNA target regions (Figure 1B).

crd1 / rcd1b Test: A small deletion in PDE6B gene has been identified that is associated with the rcd1b disease in the American Staffordshire Terrier breed (2).