Sentences with phrase «small macromolecular»
«If this is to be any serious use, I suspect it will be in collaboration with existing super-resolution techniques, on small macromolecular complexes, to push the boundaries a bit further, rather than looking at whole cells.»
https://www.scientificamerican.com/ Not exact matches
The pair are corresponding authors on a paper appearing online on Feb 2 in the journal Small titled «Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.»
Neela Yennawar, director of the Huck Institute's Macromolecular X-ray Facility at Penn State and a co-author on the paper in Small, said «Crystallographers are pushing the boundary of biological samples being studied and moving towards more difficult targets of higher molecular weight and complexity.
A partial list would include the Patterson function, isomorphous replacement, and anomalous scattering, which enabled the determination of organic structures; direct (i.e., purely computational) methods of phase determination, which enabled small - molecule crystallography to be almost totally automated; synchrotron radiation and area detectors, which together made it possible to collect data on macromolecular structures in hours instead of months; and automatic interpretation of electron density maps.
The power and glory of X-ray crystallography were that it was the first technique to show our eyes what the atomic world really looked like — initially for minerals and simple solids; then for small organic substances; eventually for giant molecules, macromolecular assemblies, and even organelles like the ribosome.
Functional regulation of cystic fibrosis transmembrane conductance regulator - containing macromolecular complexes: a small - molecule inhibitor approach.
The Synchrotron Crystallography team works in close collaboration with the Structural Biology Group of the European Synchrotron Radiation Facility (ESRF) in the design, construction and operation of macromolecular crystallography (MX) and biological small angle X-ray scattering (bioSAXS) beamlines.