Sentences with phrase «small molecule drug discoveries»

«We are very excited about the prospect of using these more physiologically relevant cell - based models for gene and small molecule drug discoveries,» says Dr. Andrew Liu, Assistant Professor of Biology at the University of Memphis.

But, says Michael Varney, head of the small molecule drug discovery group at Genentech, those hiring trends are about to change: «For us, over the next 3 years, we'll hire more medicinal chemists and more process and scale - up chemists than we will analytical chemists.»

«Our strength is our patient focus,» asserts Mike Varney, senior vice president, small molecule drug discovery.

The consolidation of these efforts in an independent initiative will allow faculty from the CMI to lead a focused investigation in small molecule drug discovery for multiple therapeutic applications.

The initiative will also allow the CMI to foster new partnerships between academia and industry, and utilize the individual strengths that each possess to expedite the early stages of small molecule drug discovery.

In its inaugural collaboration that focuses on small molecule drug discovery, IACS has signed an exclusive agreement with TESARO, Inc., an oncology - focused biopharmaceutical company.

He served as Laboratory Director at biotech company, Prosetta Corporation, leading several small molecule drug discovery programs focused on viruses of interest to the United States Department of Defense.

Not exact matches

SOUTH SAN FRANCISCO, Calif. — February 5, 2018 — FLX Bio, Inc., a biopharmaceutical company focused on the discovery and development of oral small molecule drugs to activate the immune system against cancer, today announced the appointment of senior pharmaceutical research and development executive Michael F. Giordano, M.D., to its Board of Directors.

The goal of early SMA drug discovery programs has been to identify small molecules that induce the SMN gene to produce sufficient levels of protein to improve motor neuron functioning in affected patients.

Those features present significant challenges in drug discovery, and in fact, DNA - binding proteins traditionally have been considered to be beyond the reach of even small molecule inhibitors.

The process of drug discovery has been dominated in recent years by the screening of large libraries of structurally diverse small molecules for effects on target proteins associated with disease.

Arguably, the most economical and efficient strategy for development of small molecules with regenerative medicine applications is to use non-mammalian animal models for both target - and phenotype - based drug discovery.

SOUTH PLAINFIELD, NJ — December 6, 2007 — PTC Therapeutics, Inc. (PTC), a biopharmaceutical company focused on the discovery, development, and commercialization of small - molecule drugs targeting post-transcriptional control mechanisms, today announced an expanded research collaboration with the Spinal Muscular Atrophy (SMA) Foundation.

UniChem supports the integration of high - throughput screening data on small molecules with chemical libraries and chemical resources for drug discovery and optimization.

PTC is a biopharmaceutical company focused on the discovery, development and commercialization of orally administered, proprietary, small - molecule drugs that target post-transcriptional control processes.

Joshua is an organic / medicinal chemist with many years of experience in small - molecule drug discovery.

Stanford University School of Medicine Accelerating drug discovery with iPS cells and small molecule screen

An emerging strategy in early drug discovery entails using fragments, i.e. molecules smaller than conventional drug candidates, as starting points for design of novel therapeutic compounds.

A feature article in the same issue of Science provides a perspective on this research «The Synthesis Machine: An automatic device that makes small organic molecules could revolutionize drug discovery» (full text courtesy of Burke Lab).)

In more current, but not yet published work, Sattler is also fusing NMR and crystallography in a drug discovery project to find small molecule inhibitors that neutralize trypanosoma, parasites that cause sleeping sickness, by disrupting life - critical protein - protein interactions.

PTC is a biopharmaceutical company focused on the discovery and development of orally administered, proprietary small - molecule drugs that target post-transcriptional control processes.

About PTC Therapeutics PTC is a biopharmaceutical company focused on the discovery and development of orally administered, proprietary small molecule drugs that target post-transcriptional control processes.

The project that is farthest along involves the discovery of small molecules for use in combination with drugs of last resort for extensively drug - resistant tuberculosis infections.

The Alzheimer's Innovation Award will help advance particularly critical components of Mucke's ongoing drug discovery program to identify and optimize small molecule compounds that potently and safely reduce tau levels in the brain.

Carmot's vision is to become a leader in drug discovery by unlocking novel therapeutic target space not currently accessible to conventional small molecule technologies.

Chemotype Evolution thus provides an efficient and systematic approach for converting peptides into small molecules, a goal that has remained a significant challenge in drug discovery.

PTC Therapeutics Inc., is a biopharmaceutical company focused on the discovery and development of orally administered, proprietary small - molecule drugs that target post-transcriptional control processes.

Tags for this Online Resume: high throughput screening, cell culture, data, assay development, drug discovery, label - free, Biacore, Perkin Elmer, small molecule, hit - to - lead, ion channel, GPCR, enzyme, enzymatic, assay

Accomplishments: * Actively consulting on, discovery and development of Antibody Drug Conjugates (ADCs) * Actively consulting on, small molecules process optimization, scale - up and regulatory aspects * Sepsis diagnostic kits (mAb based) business to Asia for development, manuf.

I am interested in Scientist position for designing and developing novel small molecules, developing new synthetic routes and process optimization, for drug discovery and development.