Sentences with phrase «small molecule drugs called»

Not exact matches

The new research, published recently as two separate studies in ACS Central Science and the Journal of the American Chemical Society, demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

The researchers behind the new study, from Winston - Salem State University in the US and Universiti Malaysia Sarawak in Malaysia, have found that adding similar, but smaller polycationic molecules onto a new kind of material called carbon nanodots makes them even better at killing drug - resistant bacteria.

By studying the regulation of the clock proteins called Period (PER) and Cryptochrome (CRY)-- proteins that are thought to be involved with metabolism — St. John and Doyle were able to model the mechanisms of two small - molecule drugs — Longdaysin and KL0001 — that regulate the expression of the clock proteins.

Scientists already have a drug that can curb Brd4's actions — a small molecule called JQ1 that prevents Brd4 from binding to chromatin.

The new drug, a small molecule called anle138b, blocks these pores from moving ions in and out of nerve cells.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

The majority of drugs that humans use to treat the variety of ailments we suffer are so - called «small molecules.»

Efforts to inhibit this enzyme, called β - secretase 1 (BACE1), with small molecule drugs have met with limited success so far, says Ryan Watts, a neurobiologist at the biotech company Genentech in South San Francisco, California, and one of the leaders of the new research.

Engineered G protein - coupled receptors (GPCRs) called RASSLs (receptors activated by small synthetic ligands) that are unresponsive to endogenous natural hormones but can still be activated via synthetic small - molecule drugs.

«We have provided evidence, in collaboration with Erich Wanker from Berlin, that such activation can be achieved, in principle, with an experimental small molecule drug [called] geldanamycin.

Then for postdoctoral research I moved to Yale University, where I worked in a lab that looked at all kinds of different disease areas using the approaches of a field called chemical biology, which is using small molecules — chemicals — to probe biological systems in the hopes of developing compounds that could be new drugs.

«In our previous work, we found that a drug - like small molecule called JQ1 can prevent the development of heart failure in mouse models when administered at the very onset of the disease.

The team screened a small molecule compound library and identify a drug, which they call CLP257.

As the drug enters your system, it breaks down itself into small molecules that is enough to pass through your body's cell mainly because as mentioned earlier, every cell in our body have receptors for steroids called androgen receptor which is where the steroid molecules bind.

As the drug enters your system, it breaks down itself into small molecules that is enough to pass through your body's cell mainly because as mentioned earlier, every cell in our body have receptors for steroids called

Its pharmaceutical products include chemically - synthesized drugs or small molecules and an increasing portion of products produced from biological processes called biologics.